DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and aqrs

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_651632.2	Gene:	aqrs / 43396	FlyBaseID:	FBgn0039598	Length:	366	Species:	Drosophila melanogaster

Alignment Length:	216	Identity:	52/216 - (24%)
Similarity:	88/216 - (40%)	Gaps:	60/216 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 CGGSLISTRYVITASHCVNGKALPTDWR--------LSGVRLGEWDTNTNPDCEVDVRGMKDCAP 214
            |.|:|||.|.|:|::||...:.....:.        |:||.|.:     ||:
  Fly    89 CAGALISRRMVVTSTHCFQPRRFDLIYEYTAKHLSILTGVELDD-----NPE------------- 135

  Fly   215 PHLDVPVERTIPHPDYIPASKNQ--VNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITM 277
            ||..:..        ::|.:||:  .|.:|||.|:.::: .|..|.|  ||.   |.....|..:
  Fly   136 PHQVIGF--------FMPVNKNERFTNYVALLALSNKLD-RDKYRYI--PLH---RKKPQAGDDV 186

  Fly   278 DVAGWGKTE-QLSASNLKLKAAVEGFRMDECQNVYSSQDIL----LEDTQMCAGGK--EGVDSCR 335
            .:|.:|..: |:...|.::      ..:|.|:..|..:::.    .|...:|...|  ....:|.
  Fly   187 KMAYYGPPKFQIRLYNTRV------MDIDRCKIHYGLKEVFHVSTFEPDFICVRNKRHSKKTTCS 245

  Fly   336 GDSGGPLIGLDTNK---VNTY 353
            ...|.||: :| ||   :|.|
  Fly   246 TRPGDPLL-ID-NKLAAINIY 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	52/216 (24%)
		Tryp_SPc	128..389	CDD:238113	52/216 (24%)
aqrs	NP_651632.2	Trypsin	82..290	CDD:278516	52/216 (24%)
aqrs	NP_651632.2	Tryp_SPc	83..268	CDD:304450	52/216 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100