DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and CG11836

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	106/294 - (36%)
Similarity:	156/294 - (53%)	Gaps:	54/294 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 SNSLLPLPGQCGNILSN---RIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITA 171
            ::||......||  .||   ||.||..|.::::||||.|.|   .||  .||||||::..||::|
  Fly    78 NSSLKNCDCDCG--FSNEEIRIVGGKPTGVNQYPWMARIVY---DGK--FHCGGSLLTKDYVLSA 135

  Fly   172 SHCVNGKALPTDWRLSGVRL--GEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPAS 234
            :|||  |.|    |.|.:|:  |:.|.....:.:...|.            |...|.|..:.|.:
  Fly   136 AHCV--KKL----RKSKIRVIFGDHDQEITSESQAIQRA------------VTAVIKHKSFDPDT 182

  Fly   235 KNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFD--GITMDVAGWGKTE---QLSASNLK 294
            .|  ||||||||.:.:.::..::|||||      ...:|  |....|.|||:|.   :|.:...:
  Fly   183 YN--NDIALLRLRKPISFSKIIKPICLP------RYNYDPAGRIGTVVGWGRTSEGGELPSIVNQ 239

  Fly   295 LKAAVEGFRMDECQNV-YSSQDILLEDTQMCAGGKEGVDSCRGDSGGPLIGLDTNKVNTYYFLAG 358
            :|..:  ..:.||:|. |.|..|  ..:.:|| |:..:|||:|||||||  |.:|.|.  ||:.|
  Fly   240 VKVPI--MSITECRNQRYKSTRI--TSSMLCA-GRPSMDSCQGDSGGPL--LLSNGVK--YFIVG 295

  Fly   359 VVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTIES 392
            :||:| ..||..|:||||:.|.|::.||::.:|:
  Fly   296 IVSWG-VGCGREGYPGVYSRVSKFIPWIKSNLEN 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	97/266 (36%)
		Tryp_SPc	128..389	CDD:238113	98/268 (37%)
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	98/268 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457523
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	4	3.940