DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and CG3916

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_650167.1	Gene:	CG3916 / 41484	FlyBaseID:	FBgn0038003	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	312	Identity:	74/312 - (23%)
Similarity:	123/312 - (39%)	Gaps:	100/312 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 VTSNSLLPLPGQCGNILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITAS 172
            |||.:..|          .||.||.:.. :..|:...::..: :|:..|.||||::|.::|:||:
  Fly    21 VTSTTESP----------TRINGGQRVN-ETVPFQVSLQMQR-RGRWQHFCGGSIVSGQHVLTAA 73

  Fly   173 HCVNGKAL--------PTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIP--- 226
            ||:....:        ..:|:..|:|                               .|.:.
  Fly    74 HCMEKMKVEDVSVVVGTLNWKAGGLR-------------------------------HRLVTKHV 107

  Fly   227 HPDYIPASKNQ--VNDIALLRLAQ--QVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKT-- 285
            ||.|   |.|.  :|||||:::..  ::|.:|....:     :.......:.:.:.:.|||.|
  Fly   108 HPQY---SMNPRIINDIALVKVTPPFRLERSDISTIL-----IGGSDRIGEKVPVRLTGWGSTSP 164

  Fly   286 --------EQLSASNLKL----KAAVEGFRMDECQNVYSSQDILLEDTQMCAGGKEGVDSCRGDS 338
                    :||.|.|.:.    ....:|||:..              .::||...:|..:|.|||
  Fly   165 STSSATLPDQLQALNYRTISNEDCNQKGFRVTR--------------NEICALAVQGQGACVGDS 215

  Fly   339 GGPLIGLDTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTI 390
            |||||     :......|.|:||:|.:.|. .|.|.|||.|..::.:|...|
  Fly   216 GGPLI-----RPGKQPHLVGIVSYGSSTCA-QGRPDVYTRVSSFLPYISQVI 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	68/287 (24%)
		Tryp_SPc	128..389	CDD:238113	68/289 (24%)
CG3916	NP_650167.1	Tryp_SPc	30..257	CDD:214473	68/287 (24%)
CG3916	NP_650167.1	Tryp_SPc	31..260	CDD:238113	68/289 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010