DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and CG17404

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_650165.2	Gene:	CG17404 / 41482	FlyBaseID:	FBgn0038001	Length:	275	Species:	Drosophila melanogaster

Alignment Length:	312	Identity:	82/312 - (26%)
Similarity:	130/312 - (41%)	Gaps:	80/312 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LLPLPGQCGNILS--------NRIYGGMKTKIDE-FPWMALIEYTKSQGKKGHHCGGSLISTRYV 168
            ::.|.|..|.:.|        :||.||......| .|:...::| :::|.:.|.||||:|:...:
  Fly    12 VVALGGVFGRLNSRQPSGYTPHRIVGGADIPPGEHVPYQVSLQY-RTRGGQMHFCGGSIIAPNRI 75

  Fly   169 ITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGM--KDCAPPHLDVPVERTIPHPDYI 231
            :||:||..|        |:..|:         .....:||:  |......|...:     ||.|
  Fly    76 LTAAHCCQG--------LNASRM---------SVVAGIRGLNEKGSRSQVLSYSI-----HPKY- 117

  Fly   232 PASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVN--------LRSATFD----GITMDVAGWGK 284
              .:...:|:|:|.          ::|   ||.:|        .||...|    |:.:.:.|||.
  Fly   118 --QELVTSDLAVLS----------IKP---PLKLNNSTISAIEYRSQGKDFVGGGVPVTLTGWGL 167

  Fly   285 --------TEQLSASNLKLKAAVEGFRMDECQNVYSSQDILLEDTQMCAGGK-EGVDSCRGDSGG 340
                    .:.::..|:..:.:.......||:|.....   :.||::||.|. .|  :|.|||||
  Fly   168 RLPVPFPFLDNVNYPNVLQRMSYHTISNSECRNAGMES---VTDTEICARGPFRG--ACSGDSGG 227

  Fly   341 PLIGLDTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTIES 392
            ||:....|.:..    .|:||:|...|||...|.|||.|..:.|||.|..:|
  Fly   228 PLVMESKNGLQQ----VGIVSYGLVVCGLYISPDVYTRVSTFSDWIGNQTKS 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	74/282 (26%)
		Tryp_SPc	128..389	CDD:238113	75/284 (26%)
CG17404	NP_650165.2	Tryp_SPc	34..269	CDD:214473	74/282 (26%)
CG17404	NP_650165.2	Tryp_SPc	35..269	CDD:238113	73/281 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010