DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and CG4613

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001261841.1	Gene:	CG4613 / 39586	FlyBaseID:	FBgn0036427	Length:	374	Species:	Drosophila melanogaster

Alignment Length:	361	Identity:	118/361 - (32%)
Similarity:	163/361 - (45%)	Gaps:	106/361 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 SSSETTPPP----------------------------KPNVTSNSL------------LPLPG-- 118
            ::|.|.|||                            .|:.|::||            .||.|
  Fly    51 TTSSTGPPPGVQSDFIDDLIEGHKQQILSNVLGVASETPSDTASSLGSTSLSSSASPVFPLEGGG 115

  Fly   119 ------------QCGNILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGH--HCGGSLISTRYVI 169
                        .||....|||.||.:.:.:::||:|.|       .:|.  .|||:||:.|||:
  Fly   116 AKAFRVNRCASCTCGVPNVNRIVGGTQVRTNKYPWIAQI-------IRGTFLFCGGTLINDRYVL 173

  Fly   170 TASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTI----PHPDY 230
            ||:|||:|    .|.|...|||.:.|.::.                ||.  |.|::    .|..|
  Fly   174 TAAHCVHG----MDMRGVSVRLLQLDRSST----------------HLG--VTRSVAFAHAHVGY 216

  Fly   231 IPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKTEQ-LSASNLK 294
            .|.|  .|:|||||||.|.:...|.:||.|||.:   ....||.....|||||.::: .|.|::.
  Fly   217 DPVS--LVHDIALLRLDQPIPLVDTMRPACLPSN---WLQNFDFQKAIVAGWGLSQEGGSTSSVL 276

  Fly   295 LKAAVEGFRMDECQNVYSSQDILLEDTQMCAGGKE--GVDSCRGDSGGPLIGLDTNKVNTYYFLA 357
            .:..|......:|:  .:|...::.||.||||..:  |.|:|:||||||||..|     ..:.||
  Fly   277 QEVVVPIITNAQCR--ATSYRSMIVDTMMCAGYVKTGGRDACQGDSGGPLIVRD-----RIFRLA 334

  Fly   358 GVVSFGPTPCGLAGWPGVYTLVGKYVDWIQ-NTIES 392
            |||||| ..|.....|||||.|.:|::||. ||.:|
  Fly   335 GVVSFG-YGCAKPDAPGVYTRVSRYLEWIAVNTRDS 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	98/267 (37%)
		Tryp_SPc	128..389	CDD:238113	99/270 (37%)
CG4613	NP_001261841.1	Tryp_SPc	136..362	CDD:214473	98/267 (37%)
CG4613	NP_001261841.1	Tryp_SPc	137..362	CDD:238113	97/266 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457526
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	4	3.940