DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and Prss33

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_017173005.1	Gene:	Prss33 / 353130	MGIID:	2661234	Length:	341	Species:	Mus musculus

Alignment Length:	315	Identity:	104/315 - (33%)
Similarity:	149/315 - (47%)	Gaps:	58/315 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 ESSSETTPPPKPNVTSNSLLPLP------GQCGN-ILSNRIYGGMKTKIDEFPWMALIEYTKSQG 152
            ::|||.|.....::....||.|.      ..||. .:|:||.||...:..|:||.     |..|.
Mouse    58 QASSEDTMRGASHLQILLLLVLGTRMQECAACGQPRMSSRIVGGRDAQDGEWPWQ-----TSIQH 117

  Fly   153 KKGHHCGGSLISTRYVITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHL 217
            :..|.||||||:.::|:||.||...:..|:::   .|.||.        ..:|||...:     |
Mouse   118 RGAHVCGGSLIAPQWVLTAGHCFPRRVWPSEY---SVLLGA--------LSLDVRSSHE-----L 166

  Fly   218 DVPVERTIPHPDYIPASKNQV-NDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAG 281
            .|||.|.:..|||   |:::. .|:|||:|...|..:..::|:|||..   .|....|....|.|
Mouse   167 LVPVLRVLLPPDY---SEDEARGDLALLQLRHPVSLSTRIQPVCLPAP---GSHPPPGSPCWVTG 225

  Fly   282 WGKTEQLSAS-NLKLKAAVEGFRMD-----ECQNVY-------SSQDILLEDTQMCAGGKEG-VD 332
            ||   .||.. .|.....::|.|:.     .|..:|       ..:.|:|.. .:|||.:.| .|
Mouse   226 WG---SLSPGVPLPKGRPLQGVRVPLLDSRACDRLYHVGANVPQGERIVLPG-NLCAGYRRGHKD 286

  Fly   333 SCRGDSGGPLIGLDTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQ 387
            :|:|||||||..:::.    ::.|.||||:| ..|.|...|||||.|.||..|||
Mouse   287 ACQGDSGGPLTCMESG----HWVLVGVVSWG-KGCALPNRPGVYTNVAKYSPWIQ 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	91/273 (33%)
		Tryp_SPc	128..389	CDD:238113	93/275 (34%)
Prss33	XP_017173005.1	Tryp_SPc	98..336	CDD:238113	91/273 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910