Protein Alignment ea and TMPRSS11A

DIOPT Version :10

• Sequence 1: NP_524362.2
• Gene: ea / 41858
• FlyBaseID: FBgn0000533
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_872412.3
• Gene: TMPRSS11A / 339967
• HGNCID: 27954
• Length: 421
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 94/293 - (32%)
• Similarity: 140/293 - (47%)
• Gaps: 53/293 - (18%)

  Fly   107 NVTSNSL--LPLPGQCG------NILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLI 163
            |..|:|.  |.:...||      |:  |||..|:......:||.|.::|...     |.||.:||
Human   163 NAMSSSTGELTVQASCGKRVVPLNV--NRIASGVIAPKAAWPWQASLQYDNI-----HQCGATLI 220

  Fly   164 STRYVITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHP 228
            |..:::||:||......|..|.:|      :.|..|              ||.:...|.|.|.|.
Human   221 SNTWLVTAAHCFQKYKNPHQWTVS------FGTKIN--------------PPLMKRNVRRFIIHE 265

  Fly   229 DYIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFD-GITMDVAGWGKTEQLSASN 292
            .|..|::..  |||:::::.:|.::|.:|.||||    ..||:|. .:|:.:.|:|.......|.
Human   266 KYRSAAREY--DIAVVQVSSRVTFSDDIRQICLP----EASASFQPNLTVHITGFGALYYGGESQ 324

  Fly   293 LKLK-AAVEGFRMDECQ--NVYSSQDILLEDTQMCAGGKEGV-DSCRGDSGGPLIGLDTNKVNTY 353
            ..|: |.|:....|.|:  .||.:.   ::....|||..||: |:|||||||||:   |..:...
Human   325 NDLREARVKIISDDVCKQPQVYGND---IKPGMFCAGYMEGIYDACRGDSGGPLV---TRDLKDT 383

  Fly   354 YFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWI 386
            ::|.|:||:|.. ||....|||||.|..|.:||
Human   384 WYLIGIVSWGDN-CGQKDKPGVYTQVTYYRNWI 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:463440
		Tryp_SPc	128..389	CDD:238113	85/264 (32%)
TMPRSS11A	NP_872412.3	SEA	49..149	CDD:460188
		Tryp_SPc	190..418	CDD:238113	85/264 (32%)