DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and Ser6

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_523426.1	Gene:	Ser6 / 33073	FlyBaseID:	FBgn0011834	Length:	259	Species:	Drosophila melanogaster

Alignment Length:	293	Identity:	76/293 - (25%)
Similarity:	122/293 - (41%)	Gaps:	74/293 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LLPL---PGQCGNILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITASHC 174
            :||:   ||:    |:.|:.||.....::||....:....|     |.||||:::..|::||:||
  Fly    18 VLPVQSAPGK----LNGRVVGGEDAVKNQFPHQVSLRNAGS-----HSCGGSILTRTYILTAAHC 73

  Fly   175 VNGKAL-----PTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPAS 234
            |:.:.:     |.......:|.|..|..:.        |:.        |.|...|.|.:|
  Fly    74 VSNEDVNHVITPIAAERFTIRAGSNDRFSG--------GVL--------VQVAEVIVHEEY---- 118

  Fly   235 KNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFD---GITMDVAGWGKTEQ-------LS 289
            .|.:||:|||||...:..:..::||.||        |.|   .:.:.::|||:.:.       |.
  Fly   119 GNFLNDVALLRLESPLILSASIQPIDLP--------TVDTPADVDVVISGWGRIKHQGDLPRYLQ 175

  Fly   290 ASNLKLKAAVEGFRMDECQNVYSSQDILLEDTQMCAGGKEGVDSCRGDSGGPLIGLDTNKVNTYY 354
            .:.||      .....:|:.:.   |...|. ::|...:....:|.||||||.:      .|..
  Fly   176 YNTLK------SITRQQCEELI---DFGFEG-ELCLLHQVDNGACNGDSGGPAV------YNNQ- 223

  Fly   355 FLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQ 387
             |.||..|....|| :.:|..|..|..:.|||:
  Fly   224 -LVGVAGFVVDGCG-STYPDGYARVFYFKDWIK 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	69/273 (25%)
		Tryp_SPc	128..389	CDD:238113	70/275 (25%)
Ser6	NP_523426.1	Tryp_SPc	31..253	CDD:214473	69/273 (25%)
Ser6	NP_523426.1	Tryp_SPc	32..256	CDD:238113	70/275 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457512
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840