DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and CG4653

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_573150.2	Gene:	CG4653 / 32650	FlyBaseID:	FBgn0030776	Length:	254	Species:	Drosophila melanogaster

Alignment Length:	244	Identity:	64/244 - (26%)
Similarity:	104/244 - (42%)	Gaps:	46/244 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 HHCGGSLISTRYVITASHCVN----GKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPH 216
            |.|||:||..::::||:|||:    .::.|.  :...||:|.....|....
  Fly    48 HVCGGALIREKWILTAAHCVSLGGGQQSYPA--KSYNVRVGSIQRLTGGQL-------------- 96

  Fly   217 LDVPVERTIPHPDYIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAG 281
              ||:.:.|.|.:|..:.....||:|||.|...|.......||.|..:   |.|.  |..:..:|
  Fly    97 --VPLSKIIIHTNYSSSDAVGSNDLALLELETSVVLNANTNPIDLATE---RPAA--GSQIIFSG 154

  Fly   282 WGKTE-QLSASNLKLKAAVEGFRMDECQ-NVYSSQDILLEDTQMCAG--GKEGVDSCRGDSGGPL 342
            ||.:: ..|.|::...|..:.....:|| .:|..|:.||     |..  .::....|.||:|.|.
  Fly   155 WGSSQVDGSLSHVLQVATRQSLSASDCQTELYLQQEDLL-----CLSPVDEDFAGLCSGDAGAPA 214

  Fly   343 IGLDTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWI-QNTI 390
                  ..|..  |.|:.:|..:.|| :..|..|..|.::::|| :|.:
  Fly   215 ------SYNNQ--LVGIAAFFVSGCG-SEQPDGYVDVTQHLEWINENAV 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	61/237 (26%)
		Tryp_SPc	128..389	CDD:238113	63/241 (26%)
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	63/240 (26%)
CG4653	NP_573150.2	Tryp_SPc	30..249	CDD:214473	61/237 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457509
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840