DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and CG9673

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001285346.1	Gene:	CG9673 / 32649	FlyBaseID:	FBgn0030775	Length:	261	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	88/284 - (30%)
Similarity:	128/284 - (45%)	Gaps:	54/284 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 GNILS------NRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITASHCVNGKA 179
            |.|||      .||.||......|:||.|.:.|.|:     |.|.|::|||.:::||:|||:...
  Fly    16 GLILSAEASPQGRILGGEDVAQGEYPWSASVRYNKA-----HVCSGAIISTNHILTAAHCVSSVG 75

  Fly   180 L-PTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQVNDIAL 243
            : |.|.....||||..:.......                |.|:..|.||.|    .|.::|||:
  Fly    76 ITPVDASTLAVRLGTINQYAGGSI----------------VNVKSVIIHPSY----GNFLHDIAI 120

  Fly   244 LRLAQQVEYTDFVRPICLPLDVNLRSATFD-----GITMDVAGWGKTEQLSASNLKLKAAVEGFR 303
            |.|.:.:.::|.::.|.||...:..:...|     |..:.|||||:....:||..:.||......
  Fly   121 LELDETLVFSDRIQDIALPPTTDEETEDVDAELPNGTPVYVAGWGELSDGTASYKQQKANYNTLS 185

  Fly   304 MDEC--QNVYSSQDILLEDTQMCAGGKEGVDSCRGDSGGPLIGLDTNKVNTYYFLAGVVSFGPTP 366
            ...|  :..|..:.:      :|....||...||||:|..:|  |.:||     |.|:.||...|
  Fly   186 RSLCEWEAGYGYESV------VCLSRAEGEGICRGDAGAAVI--DDDKV-----LRGLTSFNFGP 237

  Fly   367 CGLAGWPGVYTLVGKYVDWIQ-NT 389
            || :.:|.|.|.|..|:.||: ||
  Fly   238 CG-SKYPDVATRVSYYLTWIEANT 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	80/266 (30%)
		Tryp_SPc	128..389	CDD:238113	81/269 (30%)
CG9673	NP_001285346.1	Tryp_SPc	28..256	CDD:214473	80/266 (30%)
CG9673	NP_001285346.1	Tryp_SPc	29..259	CDD:238113	81/268 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010