DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and CG32523

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_728401.1	Gene:	CG32523 / 318071	FlyBaseID:	FBgn0052523	Length:	262	Species:	Drosophila melanogaster

Alignment Length:	293	Identity:	79/293 - (26%)
Similarity:	116/293 - (39%)	Gaps:	89/293 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 QCGNILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITASHCV--NGKALP 181
            |..:.:..||.||:|.|..:||....:   :.:|:  |:|||.:||..:||||.|||  ....:|
  Fly    28 QSESAIEPRIVGGIKAKQGQFPHQISL---RLRGE--HYCGGVIISATHVITAGHCVKHGNDVVP 87

  Fly   182 TD-WRL---------SGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKN 236
            .| |.:         .|||                            :||...|.||:|.....
  Fly    88 ADLWSIQAGSLLLSSDGVR----------------------------IPVAEVIMHPNYATGGH- 123

  Fly   237 QVNDIALLRLAQQVEYTDFVRPICLPLDVNLRS---ATFDG---ITMDVAGWGK-TEQLSASNLK 294
              ||:|:|||...           |..|.|:.:   ||.|.   :.:|::|||. .|:...|:..
  Fly   124 --NDLAVLRLQSP-----------LTFDANIAAIQLATEDPPNCVAVDISGWGNIAEKGPLSDSL 175

  Fly   295 LKAAVEGFRMDECQNVYSSQDILLEDTQMCAGGKEGVDSCRGDSGGP------LIGLDTNKVNTY 353
            |...|.......|:.::.|:   |.:|.:|....:...:|.||||||      ::||.:
  Fly   176 LFVQVTSISRGACRWMFYSR---LPETMICLLHSKNSGACYGDSGGPATYGGKVVGLAS------ 231

  Fly   354 YFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWI 386
            ..|.|       .||.|. |..|..:.|...||
  Fly   232 LLLGG-------GCGRAA-PDGYLRISKVRAWI 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	76/283 (27%)
		Tryp_SPc	128..389	CDD:238113	77/284 (27%)
CG32523	NP_728401.1	Tryp_SPc	36..256	CDD:214473	76/283 (27%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	63/231 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457513
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840