Protein Alignment ea and TMPRSS11E

DIOPT Version :10

• Sequence 1: NP_524362.2
• Gene: ea / 41858
• FlyBaseID: FBgn0000533
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_054777.2
• Gene: TMPRSS11E / 28983
• HGNCID: 24465
• Length: 423
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 101/367 - (27%)
• Similarity: 153/367 - (41%)
• Gaps: 86/367 - (23%)

  Fly    63 TPLRD----TDRLYLSRSQCGYTNGKVLICCPDRY-----------------RESSSETTPPPKP 106
            :|||:    :..:..|:.:.|.....:|||   |:                 .|...:...|||.
Human    94 SPLREEFVKSQVIKFSQQKHGVLAHMLLIC---RFHSTEDPETVDKIVQLVLHEKLQDAVGPPKV 155

  Fly   107 NVTSNSLLP---------LPGQCGNILSN------RIYGGMKTKIDEFPWMALIEYTKSQGKKGH 156
            :..|..:..         |...||...|.      ||.||.:.:..|:||.|.:::..|     |
Human   156 DPHSVKIKKINKTETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGS-----H 215

  Fly   157 HCGGSLISTRYVITASHCVNGKALPTDWRLS-GVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVP 220
            .||.:||:..::::|:||......|..|..| ||.:                     .|..:...
Human   216 RCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI---------------------KPSKMKRG 259

  Fly   221 VERTIPHPDYIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFD---GITMDVAGW 282
            :.|.|.|..|...|.:.  ||:|..|:..|.||:.|..:|||      .|:::   |..|.|.|:
Human   260 LRRIIVHEKYKHPSHDY--DISLAELSSPVPYTNAVHRVCLP------DASYEFQPGDVMFVTGF 316

  Fly   283 G--KTEQLSASNLKLKAAVEGFRMDECQNVYSSQDILLEDTQMCAGGKEG-VDSCRGDSGGPLIG 344
            |  |.:..|.::|: :|.|.......|....:..| .:....:|||..|| .|:|:|||||||:.
Human   317 GALKNDGYSQNHLR-QAQVTLIDATTCNEPQAYND-AITPRMLCAGSLEGKTDACQGDSGGPLVS 379

  Fly   345 LDTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWI 386
            .|...:   ::|||:||:| ..|.....|||||.|....|||
Human   380 SDARDI---WYLAGIVSWG-DECAKPNKPGVYTRVTALRDWI 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:463440	7/29 (24%)
		Tryp_SPc	128..389	CDD:238113	82/266 (31%)
TMPRSS11E	NP_054777.2	SEA	51..147	CDD:460188	10/55 (18%)
		Tryp_SPc	192..420	CDD:238113	82/266 (31%)