DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and Prss34

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001099242.1	Gene:	Prss34 / 287140	RGDID:	1306667	Length:	316	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	98/311 - (31%)
Similarity:	132/311 - (42%)	Gaps:	81/311 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 SLLPLPGQCGNILSNRIYGGMKTKIDEFPW-MALIEYTKSQGKKGHHCGGSLISTRYVITASHCV 175
            |.:||....|..|.. |.||.......||| ::|..|.....|..|.||||||..::|:||:|||
  Rat    18 STMPLTPDSGQELVG-IVGGCPVSASRFPWQVSLRFYNMKLSKWEHICGGSLIHPQWVLTAAHCV 81

  Fly   176 NGKALPTDW---RLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDY-----IP 232
            ..|.:....   ::..:||.|.|           :.||          |.:.|.||.:     .|
  Rat    82 ELKEMEASCFRVQVGQLRLYEND-----------QLMK----------VAKIIRHPKFSEKLSAP 125

  Fly   233 ASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKTEQLSASNLKLKA 297
            ...    |||||:|...|..::.|.|:.||......|:.   .|..|||||
  Rat   126 GGA----DIALLKLDSTVVLSERVHPVSLPAASQRISSK---KTWWVAGWG-------------- 169

  Fly   298 AVEGFR-----------------MDECQ---NVYSSQD---ILLEDTQMCAGGKEGVDSCRGDSG 339
            .:||.|                 ..:|:   ..|||.|   .:::|..:|| |.||.|||:.|||
  Rat   170 VIEGHRPLPPPCHLREVAVPIVGNSDCEQKYRTYSSLDRTTKIIKDDMLCA-GMEGRDSCQADSG 233

  Fly   340 GPLIGLDTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTI 390
            |||:    .:.|..:...||||:| ..|||..:|||||.|..|:.||...:
  Rat   234 GPLV----CRWNCSWVQVGVVSWG-IGCGLPDFPGVYTRVMSYLSWIHGYV 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	91/290 (31%)
		Tryp_SPc	128..389	CDD:238113	93/292 (32%)
Prss34	NP_001099242.1	Tryp_SPc	33..276	CDD:238113	92/290 (32%)
Prss34	NP_001099242.1	Tryp_SPc	33..275	CDD:214473	91/289 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910