DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ea and Prss29

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_017453326.1	Gene:	Prss29 / 287136	RGDID:	1305856	Length:	279	Species:	Rattus norvegicus

Alignment Length:	297	Identity:	89/297 - (29%)
Similarity:	137/297 - (46%)	Gaps:	50/297 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 NSLLPLPGQCGNILSNRIYGGMKTKIDEFPW-MALIEYTKSQGKKGHHCGGSLISTRYVITASHC 174
            :|:..:|......:...|.||......::|| ::|..|..:.....|.||||:|..::|:||:||
  Rat    14 SSIAGIPASVPEDVLVGIVGGNSAPQGKWPWQVSLRVYRYNWASWVHICGGSIIHPQWVLTAAHC 78

  Fly   175 VN-GKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQV 238
            :: ..|.|:.:|   :.||          :|.:.|.:..      :.|.|.|.|||::.:...
  Rat    79 IHESDADPSAFR---IYLG----------QVYLYGGEKL------LKVSRVIIHPDFVRSGLG-- 122

  Fly   239 NDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMD---VAGWGKT---EQLSASNLKLKA 297
            :|:|||:|||.|.....|:|      |.|..|:.:....|   |.|||..   |.|.......:.
  Rat   123 SDVALLQLAQSVRSFPNVKP------VKLSPASLEVTKKDVCWVTGWGSVSMHESLPPPYRLQQV 181

  Fly   298 AVEGFRMDECQNVYSS--------QDILLEDTQMCAGGKEGVDSCRGDSGGPLIGLDTNKVNTYY 354
            .|:......|:.:|.:        |.::|:| .:|| |..|.|||.|||||||:    ..|...:
  Rat   182 QVKIVDNTLCEKLYRNATRLSNHGQRLILQD-MLCA-GSHGRDSCYGDSGGPLV----CNVTGSW 240

  Fly   355 FLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTIE 391
            .|.||||:| ..|.|...||||..|..::.||...::
  Rat   241 TLVGVVSWG-YGCALKDIPGVYARVQFFLPWITGQMQ 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	85/274 (31%)
		Tryp_SPc	128..389	CDD:238113	87/276 (32%)
Prss29	XP_017453326.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346345
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840