DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ea and CG33225

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001286682.1	Gene:	CG33225 / 2768860	FlyBaseID:	FBgn0053225	Length:	307	Species:	Drosophila melanogaster

Alignment Length:	298	Identity:	99/298 - (33%)
Similarity:	139/298 - (46%)	Gaps:	68/298 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 LPGQCGNILS----NRIYGGMKTKIDEF--PWMALIEYTKSQGKKGHHCGGSLISTRYVITASHC 174
            |...||....    .|:.||  ...|.|  |||.::     .|:....|.||||:..:|:|::.|
  Fly    41 LTNDCGTTRHPSRIRRVVGG--NDADRFANPWMVMV-----LGENNVFCSGSLITRLFVLTSASC 98

  Fly   175 VNGKALPTDWRLSGVRLGEWDTN-TNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDY-IPASKNQ 237
            :  .:||..     |.|||:|.| |:.|| ..:|.:.|         :::.|.|..: :...|..
  Fly    99 L--LSLPKQ-----VILGEYDRNCTSADC-TSIRQVID---------IDQKIIHGQFGLETVKKY 146

  Fly   238 VNDIALLRLAQQVEYTDFVRPICLPLDVNL-RSATFDGITMDVAGWGKTEQLSASNLKLKAAVEG 301
              ||||||||::|..:|:||||||.:|..: ||...    ....|||.||....|.:.....:..
  Fly   147 --DIALLRLAKKVSISDYVRPICLSVDRQVGRSVQH----FTATGWGTTEWNEPSTILQTVTLSK 205

  Fly   302 FRMDEC-----QNVYSSQDILLEDTQMCAGGKEGVDSCRGDSGGPL---IGLD-----TNKVNTY 353
            .....|     ||:.:|        |:|.||.. .|:|.||:||||   :.:|     .||...
  Fly   206 INRKYCKGRLRQNIDAS--------QLCVGGPR-KDTCSGDAGGPLSLTLKIDGDGKWNNKSRA- 260

  Fly   354 YFLAGVVSFGPTPC-GLAGWPGVYTLVGKYVDWIQNTI 390
             ||.|:||:|.:.| |:    ||||.|..|:|||..||
  Fly   261 -FLIGIVSYGSSSCSGI----GVYTNVEHYMDWIVRTI 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	92/277 (33%)
		Tryp_SPc	128..389	CDD:238113	93/279 (33%)
CG33225	NP_001286682.1	Tryp_SPc	56..289	CDD:214473	92/277 (33%)
CG33225	NP_001286682.1	Tryp_SPc	57..292	CDD:238113	93/279 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010