Protein Alignment ea and TPSG1

DIOPT Version :10

• Sequence 1: NP_524362.2
• Gene: ea / 41858
• FlyBaseID: FBgn0000533
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_036599.4
• Gene: TPSG1 / 25823
• HGNCID: 14134
• Length: 321
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 94/298 - (31%)
• Similarity: 134/298 - (44%)
• Gaps: 56/298 - (18%)

  Fly   106 PNVTSNSLLPLPGQCG----NILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTR 166
            |.|:..:|.|   .||    :....||.||.......:||.|.:..     ::.|.|||||:|.:
Human    15 PGVSLRTLQP---GCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRL-----RRVHVCGGSLLSPQ 71

  Fly   167 YVITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPH--PD 229
            :|:||:||.:|....:|::   |.|||.:...:               ||... |.:.|.|  |.
Human    72 WVLTAAHCFSGSLNSSDYQ---VHLGELEITLS---------------PHFST-VRQIILHSSPS 117

  Fly   230 YIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFD---GITMDVAGWGKT---EQL 288
            ..|.:.   .||||:.|:..|..:..:.|:|||      .|:.|   ||...|.|||.|   |.|
Human   118 GQPGTS---GDIALVELSVPVTLSSRILPVCLP------EASDDFCPGIRCWVTGWGYTREGEPL 173

  Fly   289 SASNLKLKAAVEGFRMDECQNVYSSQ-DILLEDTQMCAGGKEGVDSCRGDSGGPLIGLDTNKVNT 352
            .......:..|.....:.|:..|... ..:|:...:||.|..  |:|:.||||||:    .:||.
Human   174 PPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCARGPG--DACQDDSGGPLV----CQVNG 232

  Fly   353 YYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTI 390
            .:..||.||:| ..||....|||||.|..||:||:..|
Human   233 AWVQAGTVSWG-EGCGRPNRPGVYTRVPAYVNWIRRHI 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:463440
		Tryp_SPc	128..389	CDD:238113	86/269 (32%)
TPSG1	NP_036599.4	Tryp_SPc	38..268	CDD:238113	86/269 (32%)