DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and CG30289

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_726081.1	Gene:	CG30289 / 246532	FlyBaseID:	FBgn0050289	Length:	316	Species:	Drosophila melanogaster

Alignment Length:	297	Identity:	103/297 - (34%)
Similarity:	153/297 - (51%)	Gaps:	58/297 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 NVTSNSLLPLPGQCGNILSN------RIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLIST 165
            ||.|..|:.   .||  :|.      .|:||.||.|.|.|||.|:..:|.       ||||||:.
  Fly    20 NVMSRLLVE---NCG--ISKDDPYVPNIFGGAKTNIQENPWMVLVWSSKP-------CGGSLIAR 72

  Fly   166 RYVITASHCVNGKALPTDWRLSGVRLGEWDT-NTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPD 229
            ::|:||:|||:.:.|       .||||:::| :..|.|.     ...|.|...::.|:..|.|.:
  Fly    73 QFVLTAAHCVSFEDL-------YVRLGDYETLDPMPYCL-----NNHCIPKFYNISVDMKIVHEN 125

  Fly   230 YIPASKNQV---NDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKTEQLSAS 291
            |     |.:   |||||||:::.|||:|:||||||.:...::|...    ..|.|||:||....|
  Fly   126 Y-----NGITLQNDIALLRMSEAVEYSDYVRPICLLVGEQMQSIPM----FTVTGWGETEYGQFS 181

  Fly   292 NLKLKAAVEGFRMDECQNVYSSQDILLEDTQMCAGGKEGVDSCRGDSGGPL-----IGLDTNKVN 351
            .:.|.|.:....:..|...::.|   .:.:|:|||.... ::|:|||||||     .|   |::.
  Fly   182 RILLNATLYNMDISYCNIKFNKQ---ADRSQICAGSHTS-NTCKGDSGGPLSSKFHYG---NRLL 239

  Fly   352 TYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQN 388
            ::.:  |:||:|...|. |...||||.|..:.:||.|
  Fly   240 SFQY--GLVSYGSERCA-ANVAGVYTNVSYHREWIFN 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	93/267 (35%)
		Tryp_SPc	128..389	CDD:238113	96/270 (36%)
CG30289	NP_726081.1	Tryp_SPc	42..271	CDD:214473	93/266 (35%)
CG30289	NP_726081.1	Tryp_SPc	42..271	CDD:238113	93/266 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010