DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and CG30287

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_726083.1	Gene:	CG30287 / 246530	FlyBaseID:	FBgn0050287	Length:	284	Species:	Drosophila melanogaster

Alignment Length:	287	Identity:	96/287 - (33%)
Similarity:	138/287 - (48%)	Gaps:	49/287 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 LPGQCGNILSN----RIYGGMKTKIDEFPWMALIEYTKSQGKKG-HHCGGSLISTRYVITASHCV 175
            |..||....|.    |:..|....:...|||.:|.      ::| ..||||||:.|||:||:||.
  Fly    26 LDPQCVTARSEPGLYRVINGKPADLFSNPWMVIII------ERGMMKCGGSLITPRYVLTAAHCK 84

  Fly   176 NGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPA--SKNQV 238
            :    .|..:|: ||||::|.|...||     ....|.|...::.|.||     |:|:  :..:.
  Fly    85 S----ETKSQLT-VRLGDYDVNQAVDC-----SSYGCIPRPREINVTRT-----YVPSHYTNFRK 134

  Fly   239 NDIALLRLAQQVEYTDFVRPICLPL-DVNLRSATFDG-ITMDVAGWGKTEQLSASNLKLKAAVEG 301
            ||||||||...|:|.|.:|.|||.: |....|..... :..:..|||:||....|.:..:|::..
  Fly   135 NDIALLRLETTVQYGDNIRSICLLMGDYTWSSNILKNLVKFNTTGWGRTESRINSPVLQQASLTH 199

  Fly   302 FRMDECQNVYSSQDILLEDTQMCAGGKEGVDSCRGDSGGPL-----IGLDTNKVNTYYFLAGVVS 361
            ..:..|..|:..|   |:.:.:|.....| .:|:|||||||     ||.:...:     |.||||
  Fly   200 HHLSYCAQVFGKQ---LDKSHICVASSTG-STCQGDSGGPLTARVRIGSERRVI-----LFGVVS 255

  Fly   362 FGPTPC-GLAGWPGVYTLVGKYVDWIQ 387
            :|...| |    |.|||.|..:.:||:
  Fly   256 YGAVHCFG----PTVYTNVIHFANWIE 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	90/269 (33%)
		Tryp_SPc	128..389	CDD:238113	91/271 (34%)
CG30287	NP_726083.1	Tryp_SPc	41..277	CDD:214473	90/269 (33%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	91/271 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010