DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and CG30083

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_725492.3	Gene:	CG30083 / 246444	FlyBaseID:	FBgn0050083	Length:	279	Species:	Drosophila melanogaster

Alignment Length:	302	Identity:	83/302 - (27%)
Similarity:	129/302 - (42%)	Gaps:	69/302 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 PNVTSNSLLPLPGQCG-NILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVI 169
            |...|..|.|   .|| ..:|.:|..|...:....||||.|.....:......|||:||..::|:
  Fly    14 PGAMSQFLEP---NCGYPDISPKIMHGQNAENGTNPWMAYIFKYNDKEVAELVCGGTLIHKQFVL 75

  Fly   170 TASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPAS 234
            :|:||:...      ::..|||||..::.                               |...:
  Fly    76 SAAHCIKRD------QILAVRLGEHSSSR-------------------------------YFAVT 103

  Fly   235 K----------NQVNDIALLRLAQQVEYTDFVRPICLPLD----VNLRSATFDGITMDVAGWGKT 285
            |          :..|||.:||:...|::...:||||:..|    .|::       |...||||||
  Fly   104 KAFRNKYFTTGSYSNDIGILRIQPIVKFNAVIRPICIITDPTKVPNVK-------TFKAAGWGKT 161

  Fly   286 EQLSASNLKLKAAVEGFRMDECQNVYSSQDILLEDTQMCAGGKEGVDSCRGDSGGPLIGLDTNKV 350
            |..:.|.:.....:......||.|:..   :.:.::|:|||..:| |:|.||||||||.......
  Fly   162 ENETFSKVLKTVELNELNASECYNMLW---VNVTESQICAGHPDG-DTCAGDSGGPLIHPVYMDG 222

  Fly   351 NTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTIES 392
            :..|...|::|||.:.|..   |||||.:..::|||...:::
  Fly   223 SLRYVQLGIISFGSSLCNS---PGVYTRLSSFIDWILMVVDN 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	74/272 (27%)
		Tryp_SPc	128..389	CDD:238113	76/274 (28%)
CG30083	NP_725492.3	Tryp_SPc	33..255	CDD:214473	74/272 (27%)
CG30083	NP_725492.3	Tryp_SPc	34..255	CDD:238113	74/271 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010