DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and Prss27

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_780649.1	Gene:	Prss27 / 213171	MGIID:	2450123	Length:	328	Species:	Mus musculus

Alignment Length:	313	Identity:	100/313 - (31%)
Similarity:	151/313 - (48%)	Gaps:	63/313 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 KPNVTSNSLLPL------PG-----QCGN-ILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKG-H 156
            :|::.:..||||      .|     .||: .:.||:.||......|:||...|:      :.| |
Mouse     3 QPHIAALLLLPLLLRSGTEGARTLRACGHPKMFNRMVGGENALEGEWPWQVSIQ------RNGIH 61

  Fly   157 HCGGSLISTRYVITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAP-PH-LDV 219
            .||||||:..:|:||:||.:.   .:|..:..|.||               .:|...| || |.|
Mouse    62 FCGGSLIAPTWVLTAAHCFSN---TSDISIYQVLLG---------------ALKLQQPGPHALYV 108

  Fly   220 PVERTIPHPDYIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFD-GITMDVAGWG 283
            ||::...:|.|...:.:.  |:||:.|...|.:|:::.|:|||..    |..|: |:...|.|||
Mouse   109 PVKQVKSNPQYQGMASSA--DVALVELQGPVTFTNYILPVCLPDP----SVIFESGMNCWVTGWG 167

  Fly   284 K-TEQLSASNLKL--KAAVEGFRMDECQNVYSSQDI-------LLEDTQMCAGGKEG-VDSCRGD 337
            . :||....|.::  |.||......:|..:| ::|:       .::|..:|||..|| .|:|:||
Mouse   168 SPSEQDRLPNPRVLQKLAVPIIDTPKCNLLY-NKDVESDFQLKTIKDDMLCAGFAEGKKDACKGD 231

  Fly   338 SGGPLIGLDTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTI 390
            |||||:.|    |:..:..|||:|:| ..|.....||||..|..:..||...|
Mouse   232 SGGPLVCL----VDQSWVQAGVISWG-EGCARRNRPGVYIRVTSHHKWIHQII 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	88/273 (32%)
		Tryp_SPc	128..389	CDD:238113	89/275 (32%)
Prss27	NP_780649.1	Tryp_SPc	37..275	CDD:214473	88/273 (32%)
Prss27	NP_780649.1	Tryp_SPc	39..278	CDD:238113	89/274 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910