Protein Alignment ea and Tmprss11a

DIOPT Version :10

• Sequence 1: NP_524362.2
• Gene: ea / 41858
• FlyBaseID: FBgn0000533
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: XP_006534903.1
• Gene: Tmprss11a / 194597
• MGIID: 2684853
• Length: 392
• Species: Mus musculus
• Alignment Length: 276
• Identity: 96/276 - (34%)
• Similarity: 137/276 - (49%)
• Gaps: 47/276 - (17%)

  Fly   120 CGN----ILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITASHCVNGKAL 180
            ||.    :::|||..|.......:||...:     |....|.|||:||...:|:||:||....:.
Mouse   149 CGKRAIPLIANRIVSGNPAAKGAWPWQVSL-----QRSNIHQCGGTLIGNMWVVTAAHCFRTNSN 208

  Fly   181 PTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQVNDIALLR 245
            |..|.||      :.|..|              ||.:...|.|.|.|..|.|.:::  :||||::
Mouse   209 PRQWTLS------FGTTIN--------------PPLMKRDVRRIIMHERYRPPARD--HDIALVQ 251

  Fly   246 LAQQVEYTDFVRPICLPLDVNLRSATF-DGITMDVAGWGKTEQLSASNLKLK-AAVEGFRMDEC- 307
            .:.:|.::|.||.||||..    ||:| ...|:.:.|:|.......|..:|: |.|:....|.|
Mouse   252 FSPRVTFSDEVRRICLPEP----SASFPPNSTVYITGFGALYYGGESQNELREARVQIISNDICK 312

  Fly   308 -QNVYSSQDILLEDTQMCAGGKEG-VDSCRGDSGGPLIGLDTNKVNTYYFLAGVVSFGPTPCGLA 370
             ::||.::   ::....|||..|| .|:|||||||||:..| || :|:| |.|:||:|.. ||..
Mouse   313 KRHVYGNE---IKRGMFCAGFLEGNYDACRGDSGGPLVIRD-NK-DTWY-LIGIVSWGDN-CGQK 370

  Fly   371 GWPGVYTLVGKYVDWI 386
            ..|||||.|..|..||
Mouse   371 NKPGVYTQVTYYRHWI 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:463440
		Tryp_SPc	128..389	CDD:238113	92/264 (35%)
Tmprss11a	XP_006534903.1	SEA	42..135	CDD:460188
		Tryp_SPc	161..389	CDD:238113	92/264 (35%)