DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and Prss8

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_620191.1	Gene:	Prss8 / 192107	RGDID:	619973	Length:	342	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	89/287 - (31%)
Similarity:	139/287 - (48%)	Gaps:	54/287 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 CGNILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITASHCVNGKALPTDW 184
            ||.::..||.||...|..::||...|.|...     |.|||||:|.::|::|:||...:....::
  Rat    37 CGAVIQPRITGGGSAKPGQWPWQVSITYNGV-----HVCGGSLVSNQWVVSAAHCFPREHSKEEY 96

  Fly   185 RLSGVRLG--EWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQVNDIALLRLA 247
            .   |:||  :.|:.:| |..|..              |.:.|.|..|  ..:....||||:||:
  Rat    97 E---VKLGAHQLDSFSN-DIVVHT--------------VAQIISHSSY--REEGSQGDIALIRLS 141

  Fly   248 QQVEYTDFVRPICLPLDVNLRSATF-DGITMDVAGWGKTEQLSASNLKLKA-------AVEGFRM 304
            ..|.::.::||||||    ..:|:| :|:...|.|||..    |.::.|:.       .|.....
  Rat   142 SPVTFSRYIRPICLP----AANASFPNGLHCTVTGWGHV----APSVSLQTPRPLQQLEVPLISR 198

  Fly   305 DECQNVYSSQDI-----LLEDTQMCAG-GKEGVDSCRGDSGGPLIGLDTNKVNTYYFLAGVVSFG 363
            :.|..:|:...:     .::...:||| .|.|.|:|:|||||||    :..::..::|||:||:|
  Rat   199 ETCSCLYNINAVPEEPHTIQQDMLCAGYVKGGKDACQGDSGGPL----SCPIDGLWYLAGIVSWG 259

  Fly   364 PTPCGLAGWPGVYTLVGKYVDWIQNTI 390
            .. ||....||||||...|..||.:.:
  Rat   260 DA-CGAPNRPGVYTLTSTYASWIHHHV 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	85/274 (31%)
		Tryp_SPc	128..389	CDD:238113	86/276 (31%)
Prss8	NP_620191.1	Tryp_SPc	44..281	CDD:214473	85/274 (31%)
Prss8	NP_620191.1	Tryp_SPc	45..284	CDD:238113	86/276 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910