DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and Klk1b1

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_034775.1	Gene:	Klk1b1 / 16623	MGIID:	892019	Length:	261	Species:	Mus musculus

Alignment Length:	288	Identity:	89/288 - (30%)
Similarity:	132/288 - (45%)	Gaps:	72/288 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 LSNRIYGGMKTKIDEFPW-MALIEYTKSQGKKGHHCGGSLISTRYVITASHCVNGKALPTDWRLS 187
            :.:||.||.|.:.:..|| :|:..|      |.:.|||.|:...:|:||:||...|        :
Mouse    21 VQSRIVGGFKCEKNSQPWHVAVYRY------KEYICGGVLLDANWVLTAAHCYYEK--------N 71

  Fly   188 GVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDY-IPASKNQVN--------DIAL 243
            .|.||:  .|...|        :..|...|   |.::..||.| :...:|::.        |:.|
Mouse    72 NVWLGK--NNLYQD--------EPSAQHRL---VSKSFLHPCYNMSLHRNRIQNPQDDYSYDLML 123

  Fly   244 LRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGK--------TEQLSASNLKLKAAVE 300
            |||::..:.||.|:||.||.:....     |.|...:|||.        .:.|...||||
Mouse   124 LRLSKPADITDVVKPIALPTEEPKL-----GSTCLASGWGSIIPVKFQYAKDLQCVNLKL----- 178

  Fly   301 GFRMDECQNVYSSQDILLEDTQMCAGGK-EGVDSCRGDSGGPLI--GLDTNKVNTYYFLAGVVSF 362
             ...::|...|..:   :.|..:|||.| .|.|:|:||||||||  |:          |.|:.|:
Mouse   179 -LPNEDCDKAYVQK---VTDVMLCAGVKGGGKDTCKGDSGGPLICDGV----------LQGLTSW 229

  Fly   363 GPTPCGLAGWPGVYTLVGKYVDWIQNTI 390
            |..|||....|||||.:.|:..||::|:
Mouse   230 GYNPCGEPKKPGVYTKLIKFTSWIKDTL 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	86/279 (31%)
		Tryp_SPc	128..389	CDD:238113	87/281 (31%)
Klk1b1	NP_034775.1	Tryp_SPc	24..253	CDD:214473	86/279 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000