DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and Prss29

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_444490.2	Gene:	Prss29 / 114662	MGIID:	2149952	Length:	279	Species:	Mus musculus

Alignment Length:	301	Identity:	92/301 - (30%)
Similarity:	144/301 - (47%)	Gaps:	68/301 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 PLPGQCGNILSNRIYGGMKTKIDEFPW-MALIEYTKSQGKKGHHCGGSLISTRYVITASHCVNGK 178
            |.||..|.::.  |.||......::|| ::|..|........|:||||:|..::|:||:||:..:
Mouse    20 PAPGPEGVLMG--IVGGHSAPQGKWPWQVSLRIYRYYWAFWVHNCGGSIIHPQWVLTAAHCIRER 82

  Fly   179 -ALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQVNDIA 242
             |.|:.:|   :|:|          |..:.|.|:.      :.|.|.|.|||::.|...  :|:|
Mouse    83 DADPSVFR---IRVG----------EAYLYGGKEL------LSVSRVIIHPDFVHAGLG--SDVA 126

  Fly   243 LLRLAQQVEYTDFVRPICLP---LDVNLRSATFDGITMDVAGWGKTE---------QLSASNLKL 295
            ||:||..|:....|:|:.||   |:|..:...:      |.|||...         :|....:|:
Mouse   127 LLQLAVSVQSFPNVKPVKLPSESLEVTKKDVCW------VTGWGAVSTHRSLPPPYRLQQVQVKI 185

  Fly   296 KAAVEGFRMDE--CQNVYSS--------QDILLEDTQMCAGGKEGVDSCRGDSGGPLIGLDTNKV 350
                    :|.  |:.:|.:        |.::|:| .:|| |.:|.|||.|||||||:    ..|
Mouse   186 --------IDNSLCEEMYHNATRHRNRGQKLILKD-MLCA-GNQGQDSCYGDSGGPLV----CNV 236

  Fly   351 NTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTIE 391
            ...:.|.||||:| ..|.|..:||||..|..::.||...::
Mouse   237 TGSWTLVGVVSWG-YGCALRDFPGVYARVQSFLPWITQQMQ 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	86/282 (30%)
		Tryp_SPc	128..389	CDD:238113	88/284 (31%)
Prss29	NP_444490.2	Tryp_SPc	31..274	CDD:238113	88/284 (31%)
Prss29	NP_444490.2	Tryp_SPc	31..271	CDD:214473	86/281 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842869
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840