DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ea and zgc:163079

DIOPT Version :9

Sequence 1:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001077051.2	Gene:	zgc:163079 / 100006550	ZFINID:	ZDB-GENE-030131-7428	Length:	313	Species:	Danio rerio

Alignment Length:	293	Identity:	82/293 - (27%)
Similarity:	118/293 - (40%)	Gaps:	79/293 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 CGNI-LSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVIT---------ASHC 174
            ||.. |:.:|.||:......:||.|.|..   :..:..:||||||:..:|:|         ||..
Zfish    27 CGRAPLNTKIIGGLNATQGSWPWQASINL---KATEEFYCGGSLINKGWVLTTAKVFALMPASDI 88

  Fly   175 VNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQVN 239
            |             |.||....|.:             .|..:...|.:.|.||:|.....|
Zfish    89 V-------------VYLGRQTQNGS-------------NPYEISRTVTKIIKHPNYNSLDSN--- 124

  Fly   240 DIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKTEQLSASNLKLKAAVEGFRM 304
             :|||:|:..|.::|:::|:||   ....|...||....|.|||        .|...|.||...:
Zfish   125 -LALLKLSSPVTFSDYIKPVCL---AAAGSVFVDGTASWVTGWG--------YLNRPATVEEIML 177

  Fly   305 D--------------ECQNVYSSQDILLEDTQMCAG--GKEGVDSCRGDSGGPLIGLDTNKVNTY 353
            .              ||...|..   ::.:..:|||  .::|...|.||.||||:    .|....
Zfish   178 PDVLQEVEAPIVNNFECNAAYGG---IITNKLLCAGYLNEDGKAPCAGDVGGPLV----IKQGAI 235

  Fly   354 YFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWI 386
            :..:|||..|  .|||.|:|.:|..|.:|.|||
Zfish   236 WIQSGVVVSG--YCGLPGYPTIYVRVSEYEDWI 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	77/283 (27%)
		Tryp_SPc	128..389	CDD:238113	79/284 (28%)
zgc:163079	NP_001077051.2	Tryp_SPc	35..266	CDD:214473	77/283 (27%)
zgc:163079	NP_001077051.2	Tryp_SPc	36..267	CDD:238113	79/284 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587392
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840