Protein Alignment CG6236 and Y41E3.1

DIOPT Version :9

• Sequence 1: NP_650446.2
• Gene: CG6236 / 41857
• FlyBaseID: FBgn0038318
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001041024.1
• Gene: Y41E3.1 / 178413
• WormBaseID: WBGene00012762
• Length: 682
• Species: Caenorhabditis elegans
• Alignment Length: 676
• Identity: 232/676 - (34%)
• Similarity: 358/676 - (52%)
• Gaps: 73/676 - (10%)

  Fly    27 VLNVERDLDKSLKIEIIERSIRSAVNRGECRHPHLPLDNPDIMKFYKPVERINCGEGM----DWV 87
            |..|..|.|:....:..|:...:|:...:|..|.|.::..:::.|:|....:.|.:..    :||
 Worm    56 VRTVHSDRDRHKGEDSSEKHAETALQSQKCNIPKLEINGSEVINFFKTHAPLECQKKNSIEDNWV 120

  Fly    88 MCEKSICFVRPEIASSHEDVICSYTDIIRKSDYKVRF-----GQSLRMKEPYV------LQASDF 141
                   |:       :::.|..:|:...|:..|:::     ..:.:.:||..      :..||:
 Worm   121 -------FI-------NDEAIIRFTEKRAKAKCKIQYFSRVDDNNNKYEEPVEVLDGDRMNGSDY 171

  Fly   142 VKVVCRSSSGESWFGMAHGIRDTVPRPPASNFSPNLAVLPPEAVAQAQQQMQDGATAPIYNVLMF 206
            ..:.| ....:.|..:...:.|          .|.:    .|...:.:::..|....| |||...
 Worm   172 ATISC-IQGFQKWKSILWDVND----------EPEI----HERARKMRKEQADPEKKP-YNVYFL 220

  Fly   207 GFDSLSRNAFIRKLPRTYEYLTQQLGATVLKGYNIVGDGTPQALVPLLTGFTELELPETRKRLSG 271
            ||||||:.:|.||||:|.::|.:.||:.||.||||||||||||.:|:||..||.|||.||||...
 Worm   221 GFDSLSQMSFRRKLPQTVKFLEETLGSVVLNGYNIVGDGTPQAFIPILTAQTETELPLTRKRYKN 285

  Fly   272 AGSVDS-YPMIWKDFARLGYMTSFNEDLPNVGTFTYRMTGFEAQPVDHYLRTYYVQAEHMAAESK 335
            |..||. ||.|||:::..||:|.:.||..::||||||:.||..||.|||.||.:.:.|.:   :.
 Worm   286 ANYVDDVYPFIWKNYSDKGYVTMYAEDAFSIGTFTYRLKGFRQQPTDHYTRTLFEEVEKL---ND 347

  Fly   336 PNCIGHQPDHITMLEYTKNFMLKYRDAPRFAFSFHGGLSHDSINLVGAADDDVHDWLVALKERSL 400
            .||||..|.|...|:..:.||.||.|.|||.......||||.|||||..|:|:...|..:.:..|
 Worm   348 RNCIGSIPLHRMWLQNGRQFMKKYEDVPRFLLMHQSLLSHDDINLVGVEDEDLSAHLSHMNDEGL 412

  Fly   401 LDDTILIMMADHGNRFAEVRATLQGKQEERLPFFSFVFPESFK--KRFPQEYKNFLANEHHLTTP 463
            .||:::|:|||||:|||::|.|.||:.|||:||||...|:..:  ::..:..:|...|...||:|
 Worm   413 FDDSVVIVMADHGHRFAKLRDTHQGQLEERMPFFSISLPKQLRNTEKGRKMEQNLRENAEKLTSP 477

  Fly   464 FDIHATLKHVIQLQTAVDQFGEINDPKTETSPPGIRISELARGRAMSLLDPIPSNRSCADAYIEP 528
            |||||:|..::.|....:  .|:|           |:.:.:..|::|:..|||.:|:|:.|.|||
 Worm   478 FDIHASLMDILNLSELGE--NELN-----------RMQDASSKRSLSVFKPIPVDRTCSQAGIEP 529

  Fly   529 HWCACLNWLPLQLNDSRYTG----IILKAAQSIVNAINLATVEQRQYCAPLEIHRVNWALRLQPH 589
            |||.||:|     .|:..||    :..:.|.::|..||...|.::..||||.:.::..|.:|.|.
 Worm   530 HWCTCLSW-----KDAMDTGEDRKLTRRIANAVVREINKEIVAEKDLCAPLSLAKIIDAKKLLPD 589

  Fly   590 KELLQFRTNSDRDGFLADMTGQTLVRDEMYQLQVVTMPGEGLFEASVAYSLHTFSATTKLTDISR 654
            |.||.::...|.|||:.|::|.|......|||::.|.|||.::|.::.|.:...........:|.
 Worm   590 KGLLAYKNVKDADGFVPDLSGSTKAAFAHYQLKLQTTPGEAIYEVTLFYDIVRDEVKLDFGSMSH 654

  Fly   655 VNKYGNQARCIYDRDPELRKYCYCRD 680
            |||:|:...||.|::..|..:|.|.|
 Worm   655 VNKFGDTPHCIIDKNYYLATFCVCYD 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6236	NP_650446.2	DUF229	73..581	CDD:281053	188/529 (36%)
		ALP_like	201..477	CDD:293745	135/278 (49%)
Y41E3.1	NP_001041024.1	DUF229	78..581	CDD:281053	193/553 (35%)
		ALP_like	215..491	CDD:293745	135/278 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	318	1.000	Domainoid score	I677
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14935
Inparanoid	1	1.050	393	1.000	Inparanoid score	I1130
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47945
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0016631
OrthoInspector	1	1.000	-	-		oto20691
orthoMCL	1	0.900	-	-		OOG6_104465
Panther	1	1.100	-	-	LDO	PTHR10974
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R17017
SonicParanoid	1	1.000	-	-		X13502
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.000