Protein Alignment CG14866 and ASGR2

DIOPT Version :10

• Sequence 1: NP_001138057.1
• Gene: CG14866 / 41854
• FlyBaseID: FBgn0038315
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_011522164.2
• Gene: ASGR2 / 433
• HGNCID: 743
• Length: 410
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 75/363 - (20%)
• Similarity: 119/363 - (32%)
• Gaps: 115/363 - (31%)

  Fly    64 SSSGSQRKSKDLPYMGADMGINGPLSYHSSAYKRPGNNIYITR-RI--GEAV------------- 112
            ||:|..|.|.....:       .|:|  |:....||.|..:.: |:  |..|
Human    19 SSAGLARTSPSSTLL-------SPVS--STCPSSPGFNPSLAKARVACGSQVSALHTFHSPSPQS 74

  Fly   113 ELEPHLRKPVESQS----PIVNPQFRPMTNQMLHQQHQQMQQQQQQQQLQQRQQPG--------- 164
            .|.|  .:|..|.|    ||:...|         |..||:..::......|.:.||
Human    75 NLSP--AQPSSSSSSSPGPIMAKDF---------QDIQQLSSEENDHPFHQGEGPGTRRLNPRRG 128

  Fly   165 --FL----------QQL------------FGI-------------GGSGG--GGGSGTQQQQHVR 190
              ||          |:|            |.|             .|.||  |...|.|.|..:|
Human   129 NPFLKGPPPAQPLAQRLCSMVCFSLLALSFNILLLVVICVTGSQSEGHGGQQGWARGAQLQAELR 193

  Fly   191 PVPLQQ----------QQVQQIAQQHPQQQHLVGGQPTTFRAVSENDLYLLGA-IEKLVYRVDYL 244
              .|::          .:||.|:.....    ||.:.|:..|..|.....|.| .:.|::.:.:.
Human   194 --SLKEAFSNFSSSTLTEVQAISTHGGS----VGDKITSLGAKLEKQQQDLKADHDALLFHLKHF 252

  Fly   245 ESRVRRSEQLIYYLMAGNNQKEVKDPCPANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAE 309
            ...:|.....:..|.:..:|:..   ||.|:.....:||:.:...:. |..|...|:..|:||..
Human   253 PVDLRFVACQMELLHSNGSQRTC---CPVNWVEHQGSCYWFSHSGKA-WAEAEKYCQLENAHLVV 313

  Fly   310 FEKVSENEEIMAYLLNQPTHRGRDYWLGGLNPGLLWIW 347
            .....|.:.|:.:  ..|.:.    |:|..:....|.|
Human   314 INSWEEQKFIVQH--TNPFNT----WIGLTDSDGSWKW 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14866	NP_001138057.1	CLECT	271..434	CDD:214480	18/77 (23%)
ASGR2	XP_011522164.2	Lectin_N	96..266	CDD:461106	34/184 (18%)
		CLECT_DC-SIGN_like	276..401	CDD:153060	18/77 (23%)