Protein Alignment CG14866 and CD209

DIOPT Version :10

• Sequence 1: NP_001138057.1
• Gene: CG14866 / 41854
• FlyBaseID: FBgn0038315
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_066978.1
• Gene: CD209 / 30835
• HGNCID: 1641
• Length: 404
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 55/295 - (18%)
• Similarity: 103/295 - (34%)
• Gaps: 105/295 - (35%)

  Fly   147 QMQQQQQQQQLQQRQQPGFLQQLFGIGGSGGGGGSGTQQQQHVRPVPLQQQQVQQIAQQHPQQQH 211
            ::.::.:||::.|..                     |:.:..|..:|.:.:| |:|.|:..:.:.
Human   182 ELPEKSKQQEIYQEL---------------------TRLKAAVGELPEKSKQ-QEIYQELTRLKA 224

  Fly   212 LVGGQPTTFRAVSENDLY-----LLGAIEKLVYRVDYLESRVRRSEQLIYYLMAGNNQKEVKDPC 271
            .||..|...:   :.::|     |..|:|:|.:                              ||
Human   225 AVGELPEKSK---QQEIYQELTQLKAAVERLCH------------------------------PC 256

  Fly   272 PANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAEFEKVSENEEIMAYLLNQPTHRGRDYWL 336
            |..:|....|||::::.|: ||..:.:|||.:.:.|...:...|..    :|..|.:...|..|:
Human   257 PWEWTFFQGNCYFMSNSQR-NWHDSITACKEVGAQLVVIKSAEEQN----FLQLQSSRSNRFTWM 316

  Fly   337 G--GLNPGLLWIWSNSAKPVNPNMNLTSIAMAQKGENSTAANLVDSSEQAAEEATGEDVLNNTVQ 399
            |  .||....|.|.:.: |:.|:..    ....:||.                       ||.
Human   317 GLSDLNQEGTWQWVDGS-PLLPSFK----QYWNRGEP-----------------------NNV-- 351

  Fly   400 IEGKGRCLRLSYNAGKHSYVYYGQECTSRHYYICE 434
              |:..|...|.|.      :...:|....::||:
Human   352 --GEEDCAEFSGNG------WNDDKCNLAKFWICK 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14866	NP_001138057.1	CLECT	271..434	CDD:214480	35/164 (21%)
CD209	NP_066978.1	Endocytosis signal	14..15
		Endocytosis signal. /evidence=ECO:0000255	16..18
		Endocytosis signal. /evidence=ECO:0000255	31..34
		transmembrane domain	36..59
		GumC	<53..>225	CDD:442439	10/64 (16%)
		neck domain	60..249		15/91 (16%)
		CLECT_DC-SIGN_like	256..379	CDD:153060	36/166 (22%)