Protein Alignment Tm2 and TPM3

DIOPT Version :9

• Sequence 1: NP_001262592.1
• Gene: Tm2 / 41853
• FlyBaseID: FBgn0004117
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_001351608.1
• Gene: TPM3 / 7170
• HGNCID: 12012
• Length: 285
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 130/281 - (46%)
• Similarity: 191/281 - (67%)
• Gaps: 0/281 - (0%)

  Fly     1 MDAIKKKMQAMKLEKDNAIDKADTCENQAKDANSRADKLNEEVRDLEKKFVQVEIDLVTAKEQLE 65
            |:|||||||.:||:|:||:|:|:..|.:.|.|..|:.:|.:|:..::||....|.:|....|.|:
Human     2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALK 66

  Fly    66 KANTELEEKEKLLTATESEVATQNRKVQQIEEDLEKSEERSTTAQQKLLEATQSADENNRMCKVL 130
            .|..:||..||.....|:|||:.||::|.:||:|::::||..||.|||.||.::|||:.|..||:
Human    67 DAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 131

  Fly   131 ENRSQQDEERMDQLTNQLKEARMLAEDADTKSDEVSRKLAFVEDELEVAEDRVRSGESKIMELEE 195
            |||:.:|||:|:....|||||:.:||:||.|.:||:|||..:|.:||..|:|....|||..||||
Human   132 ENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEE 196

  Fly   196 ELKVVGNSLKSLEVSEEKANQRVEEFKREMKTLSIKLKEAEQRAEHAEKQVKRLQKEVDRLEDEL 260
            |||.|.|:|||||...||.:|:.::::.|:|.|:.||||||.|||.||:.|.:|:|.:|.|||:|
Human   197 ELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKL 261

  Fly   261 GINKDRYKSLADEMDSTFAEL 281
            ...|:.:......:|.|..:|
Human   262 KCTKEEHLCTQRMLDQTLLDL 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tm2	NP_001262592.1	Tropomyosin	48..281	CDD:395200	108/232 (47%)
TPM3	NP_001351608.1	Tropomyosin	49..283	CDD:395200	109/234 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147731
Domainoid	1	1.000	247	1.000	Domainoid score	I2154
eggNOG	1	0.900	-	-		E1_KOG1003
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.959148	Normalized mean entropy	S1426
OMA	1	1.010	-	-		QHG48449
OrthoDB	1	1.010	-	-		D1576041at2759
OrthoFinder	1	1.000	-	-		FOG0002679
OrthoInspector	1	1.000	-	-		mtm8448
orthoMCL	1	0.900	-	-		OOG6_101961
Panther	1	1.100	-	-	O	PTHR19269
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X463
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.670