DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tm2 and Tpm4

DIOPT Version :9

Sequence 1:NP_001262592.1 Gene:Tm2 / 41853 FlyBaseID:FBgn0004117 Length:284 Species:Drosophila melanogaster
Sequence 2:NP_001001491.1 Gene:Tpm4 / 326618 MGIID:2449202 Length:248 Species:Mus musculus


Alignment Length:281 Identity:110/281 - (39%)
Similarity:166/281 - (59%) Gaps:42/281 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MDAIKKKMQAMKLEKDNAIDKADTCENQAKDANSRADKLNEEVRDLEKKFVQVEIDLVTAKEQLE 65
            ::|:|:|:||:              :.||.||..||..|..|:                      
Mouse     7 LEAVKRKIQAL--------------QQQADDAEDRAQGLQREL---------------------- 35

  Fly    66 KANTELEEKEKLLTATESEVATQNRKVQQIEEDLEKSEERSTTAQQKLLEATQSADENNRMCKVL 130
              :.|.|.:||    .|.:.|..||::|.:||:|::::|:..||.|.|.||.::|||:.|..||:
Mouse    36 --DGERERREK----AEGDAAALNRRIQLLEEELDRAQEQLATALQNLEEAEKAADESERGMKVI 94

  Fly   131 ENRSQQDEERMDQLTNQLKEARMLAEDADTKSDEVSRKLAFVEDELEVAEDRVRSGESKIMELEE 195
            |||:.:|||:|:.|..|||||:.:.::||.|.:||:|||..:|.||:.||:|....|.|..:|||
Mouse    95 ENRAMKDEEKMEILEMQLKEAKHITDEADRKYEEVARKLVILEGELKRAEERAEVSELKCGDLEE 159

  Fly   196 ELKVVGNSLKSLEVSEEKANQRVEEFKREMKTLSIKLKEAEQRAEHAEKQVKRLQKEVDRLEDEL 260
            |||.|.|:|||||.:.||.:::.::::.|:|.||.||||||.|||.||:.|.:|:|.:|.||::|
Mouse   160 ELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVSKLEKTIDDLEEKL 224

  Fly   261 GINKDRYKSLADEMDSTFAEL 281
            ...|:....|...:|.|..||
Mouse   225 AQAKEENVGLHQTLDQTLNEL 245

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tm2NP_001262592.1 Tropomyosin 48..281 CDD:395200 95/232 (41%)
Tpm4NP_001001491.1 Tropomyosin 12..246 CDD:278679 108/276 (39%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 18..49 13/58 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 78..97 9/18 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167837806
Domainoid 1 1.000 248 1.000 Domainoid score I2128
eggNOG 1 0.900 - - E1_KOG1003
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG48449
OrthoDB 1 1.010 - - D1576041at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - mtm8688
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR19269
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X463
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1110.820

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