DRSC/TRiP Functional Genomics Resources

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Protein Alignment MRG15 and ARID4B

DIOPT Version :9

Sequence 1:NP_001262588.1 Gene:MRG15 / 41850 FlyBaseID:FBgn0027378 Length:429 Species:Drosophila melanogaster
Sequence 2:NP_001193723.1 Gene:ARID4B / 51742 HGNCID:15550 Length:1312 Species:Homo sapiens


Alignment Length:302 Identity:64/302 - (21%)
Similarity:114/302 - (37%) Gaps:66/302 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    36 IYEAKVLKTKPDATPVEYYIHYAGWSKNWDEWVPENRVLKYNDDNV---KRRQELARQCGERSKK 97
            :|||.:..:..:...|.|.:||.||:..:|||:..:::::..|.||   |.|:::..:..:...|
Human   587 MYEASIKDSDVEGGEVLYLVHYCGWNVRYDEWIKADKIVRPADKNVPKIKHRKKIKNKLDKEKDK 651

  Fly    98 DNKKGVYIPGSAKAKKMEQMRNESRASTPSKDSNTSQSTASSTPTTSAGPGSKSEAGSTGTTTTN 162
            |.|   |.|.:.|.:         |.|.|...:|.|....|....|.|                 
Human   652 DEK---YSPKNCKLR---------RLSKPPFQTNPSPEMVSKLDLTDA----------------- 687

  Fly   163 STANSTTSRAHRKSTQSTP-----STARPGTPSDKKEDPAAAETTEEEGPVAPKKKRMSEQRPSL 222
              .||.|  ||.||.:.|.     ..:.......::||...|:..:..|....|...::..|..|
Human   688 --KNSDT--AHIKSIEITSILNGLQASESSAEDSEQEDERGAQDMDNNGKEESKIDHLTNNRNDL 748

  Fly   223 -------TGSDVAEKPLPPTTTPSTPTTEPAPCVESEEAYAAKVEVKIKIPDELKHYLTDDWYAV 280
                   :.|.:.|..:......|.|.:      :|.|.....:||..:..|    |..|:   |
Human   749 ISKEEQNSSSLLEENKVHADLVISKPVS------KSPERLRKDIEVLSEDTD----YEEDE---V 800

  Fly   281 VREHK-----LLELPAKVTVQQISEQYLAHKKSVKSTSASKE 317
            .::.|     ..:..:|..:::...:|...::.:|:.|..|:
Human   801 TKKRKDVKKDTTDKSSKPQIKRGKRRYCNTEECLKTGSPGKK 842

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MRG15NP_001262588.1 Tudor-knot 22..75 CDD:288553 12/38 (32%)
MRG 249..415 CDD:283390 14/74 (19%)
ARID4BNP_001193723.1 TUDOR 58..113 CDD:197660
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 124..166
RBB1NT 170..262 CDD:285392
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 266..306
ARID 311..394 CDD:198082
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 458..577
Antigenic epitope 465..473
Tudor-knot 571..624 CDD:288553 12/36 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 635..680 13/56 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 708..894 25/148 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 909..1212
Antigenic epitope 1130..1137
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1252..1288
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3001
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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