DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MRG15 and morf4l1

DIOPT Version :9

Sequence 1:	NP_001262588.1	Gene:	MRG15 / 41850	FlyBaseID:	FBgn0027378	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	XP_012814367.1	Gene:	morf4l1 / 496573	XenbaseID:	XB-GENE-5750240	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	404	Identity:	161/404 - (39%)
Similarity:	229/404 - (56%)	Gaps:	97/404 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ERVLCFHGPLIYEAKVLKTKPDATPVEYYIHYAGWSKNWDEWVPENRVLKYNDDNVKRRQELARQ 90
            ||||||||||:||||.:|.......|:|:|||:||:|||||||||:|||||.|.|:::::||
Frog    25 ERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQKEL--- 86

  Fly    91 CGERSKKDNKKGVYIPGSAKAKKMEQMRNESRASTPSKDSNTSQSTASSTPTTSAGPGSKSEAGS 155
              :::.:|.    |:.|..:|                                 |.||.|
Frog    87 --QKANQDQ----YVEGKMRA---------------------------------AAPGKK----- 107

  Fly   156 TGTTTTNSTANSTTSRAHRKSTQSTPSTARPGTPSDKKEDPAAAE-TTEEEGPVAPKKKRMSEQR 219
                         |:...:|:.:..       |..:|::.|.:.| ::..:.|..|:|||..
Frog   108 -------------TAALQQKNVEVK-------TKKNKQKGPGSGEGSSTSDIPQPPRKKRAR--- 149

  Fly   220 PSLTGSDVAEKPLPPTTTPSTPTTEPAPCVESEEAYAAKVEVKIKIPDELKHYLTDDWYAVVREH 284
                        :.||             |||||.:..:||||:|||:|||.:|.|||..:.|:.
Frog   150 ------------IDPT-------------VESEETFMNRVEVKVKIPEELKPWLVDDWDLITRQK 189

  Fly   285 KLLELPAKVTVQQISEQYLAHKKSVKSTSASKEVAINDVLDGIVEYFNVMLGSQLLYKFERTQYA 349
            :|..||||..|:.:.|:|..:||| :..:.:||.|:|:|:.||.||||||||:||||||||.|||
Frog   190 QLFNLPAKKNVETVLEEYATYKKS-RGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYA 253

  Fly   350 DVMQKHPDTPLSELYGSFHLLRLFVRLGSMLSYSALDQQSMQNLLTHVQDFLKFLVKNSSIFFSM 414
            |::..|||.|:|::||:.||||||||:|:||||:.||::|:..||.::.||||:|.||||:.||.
Frog   254 DILADHPDAPMSQVYGAPHLLRLFVRIGAMLSYTPLDEKSLALLLNYLHDFLKYLAKNSSLLFSA 318

  Fly   415 SNFINVDPEYVRNA 428
            |::....|||.|.|
Frog   319 SDYEVAPPEYHRKA 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MRG15	NP_001262588.1	Tudor-knot	22..75	CDD:288553	33/48 (69%)
MRG15	NP_001262588.1	MRG	249..415	CDD:283390	94/165 (57%)
morf4l1	XP_012814367.1	CBD_MSL3_like	25..81	CDD:350846	38/55 (69%)
morf4l1	XP_012814367.1	MRG	147..322	CDD:368575	98/203 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	198	1.000	Domainoid score	I3039
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H40499
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3527
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1624495at2759
OrthoFinder	1	1.000	-	-		FOG0002343
OrthoInspector	1	1.000	-	-		oto103399
Panther	1	1.100	-	-	LDO	PTHR10880
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1774
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160