DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MRG15 and Arid4a

DIOPT Version :9

Sequence 1:	NP_001262588.1	Gene:	MRG15 / 41850	FlyBaseID:	FBgn0027378	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	XP_036013289.1	Gene:	Arid4a / 238247	MGIID:	2444354	Length:	1283	Species:	Mus musculus

Alignment Length:	418	Identity:	91/418 - (21%)
Similarity:	148/418 - (35%)	Gaps:	89/418 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GEVKPAKVENYSTGTDANTLFVDGERVLCFHGPLIYEAKVLKTKPDATPVEYYIHYAGWSKNWDE 66
            ||.:....|...|||.....:..|:.      ..||||.:..|:.|...:.|.:||.||:..:||
Mouse   566 GEDEEDDTEPCLTGTKVKVKYGRGKT------QKIYEASIKSTEMDDGEILYLVHYYGWNVRYDE 624

  Fly    67 WVPENRVL---------KYNDDNVKRRQELARQC----------GERSKKDNKKGVYIPGSAKAK 112
            ||..:|::         |.....||.:..|...|          ...:|:|         |.|.:
Mouse   625 WVKADRIIWPLDKGGPKKKQKKKVKCQPCLLAHCTLGHAFCPVPAVENKED---------SEKDE 680

  Fly   113 KMEQMRNESRASTPSKDSNTSQSTASSTPTTSAGPGSKSEAGSTGTTTTNSTANST--------- 168
            |.::.|.:|:...|...|..|.:...|...||...| ||::.|:.:...:....|:
Mouse   681 KRDEERQKSKRGRPPLKSTFSPNMPYSLSKTSNSEG-KSDSCSSDSEADDQLEKSSGGEDLSPDV 744

  Fly   169 ------TSRAH-RKSTQSTPSTARPGTPSDKKEDPAAAETTEEEG--------------PVAPKK 212
                  ...|| .|..:..|........:|:.:...:...|.|.|              .|...|
Mouse   745 KEELEKNENAHDDKLDEENPKIVHISKENDRTQAQPSDTLTVEAGDSDQIVHIFGDKVDQVEEFK 809

  Fly   213 KRMSEQRPSLTGSDVAEKPLPPTTTPSTPTTEPAPCVESEEAYAAKVEV-KIKIPD-ELKHYLT- 274
            |:: |:.|...|.....|.|      |....:.:|..:.|....|..:| .::... |.|::.:
Mouse   810 KQV-EKSPKGKGRRSKTKDL------SLELIKISPFGQEEAGSEAHGDVHSLEFSSLECKNFSST 867

  Fly   275 -DDWYAVVREHKLLELPAKVTVQQISEQYLAHKKSVKSTSASKEVAIND--VLDGIVEYFNVMLG 336
             ||.....:|.|   |..|:..||..|:.|.....::.|:...:...:|  ..:|       |.|
Mouse   868 EDDIDPYEKEKK---LKRKILGQQSPEKKLRLDNGMEMTTGVSQERSDDGAGAEG-------MKG 922

  Fly   337 SQLLYKFE-RTQYADVMQKHPDTPLSEL 363
            :.:...|| ..:....:...||..|.||
Mouse   923 AHVEQHFETEGEGMPSLTAEPDQGLQEL 950

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MRG15	NP_001262588.1	Tudor-knot	22..75	CDD:288553	17/61 (28%)
MRG15	NP_001262588.1	MRG	249..415	CDD:283390	27/122 (22%)
Arid4a	XP_036013289.1	Tudor_ARID4A_rpt1	4..61	CDD:410530
		Tudor_SF	62..118	CDD:413384
		RBB1NT	170..262	CDD:400474
		ARID_ARID4A	312..397	CDD:350646
		CBD_RBP1_like	580..638	CDD:350843	18/63 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3001
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900