DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4338 and Tsr3

DIOPT Version :9

Sequence 1:	NP_650441.1	Gene:	CG4338 / 41849	FlyBaseID:	FBgn0038313	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	XP_006246058.1	Gene:	Tsr3 / 360494	RGDID:	1565744	Length:	324	Species:	Rattus norvegicus

Alignment Length:	292	Identity:	136/292 - (46%)
Similarity:	179/292 - (61%)	Gaps:	41/292 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GRNR-GKGKKGGGG-----PYRNVKANHNCARSFAQQANELASSSSSENESSDSESSGDGAQNDL 61
            ||.: .:|.|..||     |.|::.|       ||::.. .|..:|.:.|.::::|..|.|....
  Rat     2 GRKKVARGSKTEGGRVRRPPGRSLDA-------FAEEVG-AALRASVQTEEAENQSGPDPAALPC 58

  Fly    62 GQPPEFAVAMWDLNHCDPKKCSGRKLARLGLISNLRLGQKFPGLVLSPVGQLCVSPLDRDVVASS 126
                  |:|||:|.|||||:|:|||||||||:..|||.|:|.||||||||...|||.||.:||.|
  Rat    59 ------ALAMWELGHCDPKRCTGRKLARLGLVRCLRLSQRFGGLVLSPVGTQYVSPADRQLVAQS 117

  Fly   127 GVAVIDCSWAKLDETPFGRMRSPHPRLLPFLVAANPINYGKPCKLSCVEAIAATLYICGFTEEAR 191
            |:||||||||||||||||:||..|.||||:||||||:|||:|||||||||.||...|.||::.|.
  Rat   118 GIAVIDCSWAKLDETPFGKMRGSHLRLLPYLVAANPVNYGRPCKLSCVEAFAAAFCIVGFSDLAV 182

  Fly   192 WFLGKFSWGHAFLELNDKLLNAYAACKSSDEIVKVQNEYL----EKEQQERDKPRDL---RDF-- 247
            ..|.||.||..||:||.:||:.||||...:|:::.:..||    :..::|...|.|:   |:|
  Rat   183 ILLRKFKWGKGFLDLNRQLLDKYAACCGPEEVLEAEQGYLASTKDTPEEENIDPFDVDSGREFAN 247

  Fly   248 --YPTSSS----------SSSSETETEGDDED 267
              .|.:|:          .|...:|..|:|.|
  Rat   248 LNRPVASTRLPMDTDDTDESEDHSEDSGEDSD 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4338	NP_650441.1	Tsr3	69..233	CDD:224953	106/167 (63%)
		RLI	69..101	CDD:281988	22/31 (71%)
		DUF367	105..229	CDD:281963	79/123 (64%)
Tsr3	XP_006246058.1	RLI	60..92	CDD:281988	22/31 (71%)
		PRK02287	65..223	CDD:235024	102/157 (65%)
		DUF367	96..219	CDD:281963	79/122 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335375
Domainoid	1	1.000	170	1.000	Domainoid score	I3692
eggNOG	1	0.900	-	-		E1_COG2042
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6922
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3389
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1222562at2759
OrthoFinder	1	1.000	-	-		FOG0004488
OrthoInspector	1	1.000	-	-		oto98254
orthoMCL	1	0.900	-	-		OOG6_101679
Panther	1	1.100	-	-	LDO	PTHR20426
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3182
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.800