DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4338 and tsr3

DIOPT Version :9

Sequence 1:	NP_650441.1	Gene:	CG4338 / 41849	FlyBaseID:	FBgn0038313	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_593007.1	Gene:	tsr3 / 2542142	PomBaseID:	SPAC1F3.04c	Length:	288	Species:	Schizosaccharomyces pombe

Alignment Length:	243	Identity:	98/243 - (40%)
Similarity:	154/243 - (63%)	Gaps:	19/243 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 SENESSDSESSGDGAQNDLGQPPEFAVAMWDLNHCDPKKCSGRKLARLGLISNLRLGQKFPGLVL 107
            |.|..|:::....|: |...:.| ..:||||..||:|..|||::|.|||.:.|||:||||.|:|:
pombe     5 SSNRRSNAKDGFKGS-NKASKFP-LPLAMWDFGHCNPNACSGKRLERLGCVRNLRIGQKFRGVVI 67

  Fly   108 SPVGQLCVSPLDRDVVASSGVAVIDCSWAKLDETPFGRMRSPHPRLLPFLVAANPINYGKPCKLS 172
            :|.|::.|||.|::...:.|.:|::||||:::|.||.|:.....||||:|||:||:|||:|.:|:
pombe    68 TPNGKVPVSPADKEYFDNGGASVVECSWARIEEIPFSRIGGRCERLLPYLVASNPVNYGRPWRLN 132

  Fly   173 CVEAIAATLYICGFTEEARWFLGKFSWGHAFLELNDKLLNAYAACKSSDEIVKVQNEYLEK---- 233
            |.||:||.:||.|:..|||..:..|.|||:|.|:|::||:.||.|..:.:|.:.:.:|||:
pombe   133 CAEALAACMYIVGYPNEARLLMDNFKWGHSFFEVNEELLDIYAQCHDAQDIQEKEKKYLEEMEAS 197

  Fly   234 EQQERDKPRDLRDFYP-----------TSSSSSSSETETEGDDEDTKA 270
            .|::|::..|  |.:.           |||:.|:||.......|.::|
pombe   198 YQEQRNQTTD--DIWSAGNLNHKPTLNTSSTHSNSEESRSPLHEPSEA 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4338	NP_650441.1	Tsr3	69..233	CDD:224953	79/163 (48%)
		RLI	69..101	CDD:281988	18/31 (58%)
		DUF367	105..229	CDD:281963	55/123 (45%)
tsr3	NP_593007.1	Tsr3	16..195	CDD:224953	83/180 (46%)
		RLI	27..61	CDD:281988	18/33 (55%)
		DUF367	65..189	CDD:281963	55/123 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	137	1.000	Domainoid score	I1240
eggNOG	1	0.900	-	-		E1_COG2042
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	195	1.000	Inparanoid score	I1025
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004488
OrthoInspector	1	1.000	-	-		oto101856
orthoMCL	1	0.900	-	-		OOG6_101679
Panther	1	1.100	-	-	LDO	PTHR20426
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1565
SonicParanoid	1	1.000	-	-		X3182
TreeFam	1	0.960	-	-
	12	11.850