Protein Alignment CG4338 and TSR3

DIOPT Version :10

• Sequence 1: NP_650441.1
• Gene: CG4338 / 41849
• FlyBaseID: FBgn0038313
• Length: 274
• Species: Drosophila melanogaster
• Sequence 2: NP_001001410.1
• Gene: TSR3 / 115939
• HGNCID: 14175
• Length: 312
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 130/274 - (47%)
• Similarity: 172/274 - (62%)
• Gaps: 18/274 - (6%)

  Fly     6 RGKGKKGGGGPYRNVKANHNCARSFAQQANELASSSSSENESSDSESSGDGAQNDLGQPPEFAVA 70
            ||.|.:||       :..|...||....|.|:.::..:..|...::  |:|.......|  ..:|
Human     8 RGPGAEGG-------RPRHLPTRSLEAFAEEVGAALQASVEPGAAD--GEGGPGPAALP--CTLA 61

  Fly    71 MWDLNHCDPKKCSGRKLARLGLISNLRLGQKFPGLVLSPVGQLCVSPLDRDVVASSGVAVIDCSW 135
            ||:|.||||::|:|||||||||:..||||.:|.||||||||:...||.||.:||.||||||||||
Human    62 MWELGHCDPRRCTGRKLARLGLVRCLRLGHRFGGLVLSPVGKQYASPADRQLVAQSGVAVIDCSW 126

  Fly   136 AKLDETPFGRMRSPHPRLLPFLVAANPINYGKPCKLSCVEAIAATLYICGFTEEARWFLGKFSWG 200
            |:|||||||:||..|.||||:||||||:|||:|.:||||||.|||..|.||.:.|...|.||.||
Human   127 ARLDETPFGKMRGSHLRLLPYLVAANPVNYGRPYRLSCVEAFAATFCIVGFPDLAVILLRKFKWG 191

  Fly   201 HAFLELNDKLLNAYAACKSSDEIVKVQNEYL----EKEQQERDKPRDL---RDFYPTSSSSSSSE 258
            ..||:||.:||:.||||.|.:|:::.:.|:|    |..|:|...|.|:   |:|...:...:|:.
Human   192 KGFLDLNRQLLDKYAACGSPEEVLQAEQEFLANAKESPQEEEIDPFDVDSGREFGNPNRPVASTR 256

  Fly   259 TETEGDDEDTKAKP 272
            ..::.||.|....|
Human   257 LPSDTDDSDASEDP 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4338	NP_650441.1	RLI	69..101	CDD:427689	22/31 (71%)
		Ribo_biogen_C	105..231	CDD:461139	79/125 (63%)
TSR3	NP_001001410.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		6/19 (32%)
		RLI	60..92	CDD:427689	22/31 (71%)
		Ribo_biogen_C	96..222	CDD:461139	79/125 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	224..312		12/47 (26%)