DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cp190 and Iws1

DIOPT Version :9

Sequence 1:NP_524359.2 Gene:Cp190 / 41848 FlyBaseID:FBgn0000283 Length:1096 Species:Drosophila melanogaster
Sequence 2:NP_775617.1 Gene:Iws1 / 73473 MGIID:1920723 Length:766 Species:Mus musculus


Alignment Length:649 Identity:124/649 - (19%)
Similarity:226/649 - (34%) Gaps:179/649 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   544 NQSYRTKGELEAHINEVH--TDDNKQQCIYCNKVFEQELQLYRHMKS-----YHKEQALEDGIID 601
            :.|.....:.|..:.::|  ||....:....|....:..:|:|...|     .|.|....|...:
Mouse    47 HHSENETSDREDGLAKIHNGTDSENDEPSNANASDSESEELHRPKDSDSDSEEHAESPASDSENE 111

  Fly   602 ETDEEFLGSQDEEEEA----EGDEEQEPEQTGKVRILSDISLPATSAITVQQAQQEQLQEEDVEQ 662
            ..::.  ||..|.||.    ..|.|:|           ::|..|.|....:...|.|:.|.|.| 
Mouse   112 PVNQH--GSDSENEELLNGHASDSEKE-----------EVSKHAASDSEAEDTLQPQVSESDSE- 162

  Fly   663 VQQEVKFVGADGNEVELTDEQRKEILSQLNQQQAGATAGGVVMVLSEPEAEHVKQE--TDEKSLA 725
                              |..|.:.....|::.....       :|:.|:|.:.:.  :|.:|..
Mouse   163 ------------------DPPRPQASDSENEEPPKPR-------ISDSESEELPKPRVSDSESED 202

  Fly   726 GTEEEYDDSQIYSELGAADSVESAKKNIADESKE--------SIDNLEWAENLIAESE-EQSNKE 781
            ....:..||         :|.|..|..::|...|        ..::.|..:..:::|| |...|.
Mouse   203 PPRPQASDS---------ESEELPKPRVSDSESEDPPRPQASDSESEELPKPRVSDSESEDPQKG 258

  Fly   782 PKSDKPRDDISEKLKELTGDWTEDENDDDVDDKPATAELASELANKDPEPTVH----EEEDDIDL 842
            |.||...:|.|...::      .|.:|.|.::|...:|:.:|.........:|    |||:....
Mouse   259 PASDSEAEDASRHKEK------PDSDDSDGENKREDSEVQNESDGHTDRKGLHSSDSEEEEPKRQ 317

  Fly   843 ALQSLHKGPEEATEEKASEESVTSADDAVDAVPNINSQPEKM-----DVDSEAADEKASKAEVQI 902
            .:.|.....:|..|||.::.......|:.|...|.:::..::     |.||:...:|:.|.|..:
Mouse   318 KIDSDDDEEKEGDEEKVAKRKAAVLSDSEDDAGNASAKKSRVVCDADDSDSDVVSDKSGKRETTV 382

  Fly   903 KKEAELENDQEEFI---KEDSPIPHSDS---------VAELREAVTASEGEDDVHLEADNIRKEL 955
            ..::|.|..:||..   |||..:..|||         :|::.......|.|:......:::.:|.
Mouse   383 ASDSEEEAGKEESSVKKKEDKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEK 447

  Fly   956 LDELIAEAEKPDQEKDIVQSEE----NATTEALDRS----------------VTDEDDLVPPTQV 1000
            .:..:.|||..|.:.:|.:.:.    :.....|.|.                ::|.||:     |
Mouse   448 NETQLKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMCGKRRRNRDGGTFISDADDV-----V 507

  Fly  1001 STEQMEIDEPAAEKAAENNE----------------DTRTADEKEAVEDK-------------PN 1036
            |...::::|.|.|....||:                ..:..|.||...|.             |:
Mouse   508 SAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETFIDSGVMSAIKEWLSPLPD 572

  Fly  1037 QT--------------QDVTTAEKPTLESAKAG----------DEATSGEAASVDKVKSLISEW 1076
            ::              |::.:..:.||:.:..|          .|:.|.:    |....||:||
Mouse   573 RSLPALKIREELLKILQELPSVSQETLKHSGIGRAVMYLYKHPKESRSNK----DMAGKLINEW 632

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cp190NP_524359.2 BTB 20..122 CDD:279045
BTB 31..127 CDD:197585
C2H2 Zn finger 540..568 CDD:275371 5/25 (20%)
C2H2 Zn finger 569..586 CDD:275371 3/16 (19%)
Iws1NP_775617.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..466 96/472 (20%)
PHA02664 <206..317 CDD:177447 27/125 (22%)
Integrase domain-binding motif (IBM). /evidence=ECO:0000250|UniProtKB:Q96ST2 416..442 3/25 (12%)
Interaction with SUPT6H and ALYREF. /evidence=ECO:0000250 470..766 28/172 (16%)
TFIIS_I <475..739 CDD:294098 28/167 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 643..679
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167843290
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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