Protein Alignment Cp190 and IWS1

DIOPT Version :9

• Sequence 1: NP_524359.2
• Gene: Cp190 / 41848
• FlyBaseID: FBgn0000283
• Length: 1096
• Species: Drosophila melanogaster
• Sequence 2: XP_005263764.1
• Gene: IWS1 / 55677
• HGNCID: 25467
• Length: 824
• Species: Homo sapiens
• Alignment Length: 607
• Identity: 131/607 - (21%)
• Similarity: 223/607 - (36%)
• Gaps: 202/607 - (33%)

  Fly   551 GELEAHINEVHTDDNKQQCIYCNKVFEQELQLYRHMKSYHKEQALEDGIIDETDEEFLGSQDEEE 615
            |.:|.| :|..|.|.           |..|....|:.....::.|.....|...||....:|.:.
Human    48 GSVERH-SENETSDR-----------EDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDS 100

  Fly   616 EAEGDEEQEPEQTGKVRILSDISLPATSAITVQQAQQEQLQEEDVEQ------VQQEVKFVGADG 674
            |:|  |..||              ||:.:           :.|||.|      .::..|..|:|.
Human   101 ESE--ERAEP--------------PASDS-----------ENEDVNQHGSDSESEETRKLPGSDS 138

  Fly   675 NEVEL-----TDEQRKEI---------LSQLNQQQA--GATAGGVVMVLSEPEAEHVKQETDEKS 723
            ...||     :|.:.:::         :.:|.:..|  ..|...:...:|:.|:|    |.....
Human   139 ENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESE----EPPRHQ 199

  Fly   724 LAGTEEEYDDSQIYSELGAADSVESAKKNIAD-ESKE-------SIDNLEWAENLIAESEEQSNK 780
            .:.:|.|.......|:   ::|.|..|..::| ||:|       ..:|.|..:..|::||.:
Human   200 ASDSENEEPPKPRMSD---SESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESE--- 258

  Fly   781 EPKSDKPRDDISEKLKELTGDWTEDE-------NDDDVDDKPATAELASELANKD-PEPTVHEEE 837
                |.||...|:         :|:|       :|.:.:|.|...  ||:..|:: |:|.|.:.|
Human   259 ----DPPRHQASD---------SENEELPKPRISDSESEDPPRNQ--ASDSENEELPKPRVSDSE 308

  Fly   838 DDIDLALQSLHKGP--EEATEEKASEESVTSADDAVDAVPNINSQPEKMDVDSEAADEKASKAEV 900
            .      :...|||  :..||:.:..:....:||               |.|.|      :|.|
Human   309 S------EGPQKGPASDSETEDASRHKQKPESDD---------------DSDRE------NKGE- 345

  Fly   901 QIKKEAELENDQEEFIKEDSPIPHSDSVAELREAVTASEGEDDVH----LEADNIRKELLDELIA 961
                :.|::||..          ||||..: |:...:|:.|::.|    :::|...||      .
Human   346 ----DTEMQNDSF----------HSDSHMD-RKKFHSSDSEEEEHKKQKMDSDEDEKE------G 389

  Fly   962 EAEKPDQEKDIV----QSEENATTEALDRSVTDEDDLVPPTQVSTEQMEIDEPAAEKAAENNEDT 1022
            |.||..:.|..|    :.||.|:.:. .|.|:|.||             .|..|....:...|.|
Human   390 EEEKVAKRKAAVLSDSEDEEKASAKK-SRVVSDADD-------------SDSDAVSDKSGKREKT 440

  Fly  1023 RTAD-EKEA---VEDKPNQTQDVTTAEKPTLESAKAGDEATSGEAASVDKVKSLISEWGDDDED- 1082
            ..:| |:||   :.||.|:.:|:            .|.::.||.... :.:..:..|.||::|:
Human   441 IASDSEEEAGKELSDKKNEEKDL------------FGSDSESGNEEE-NLIADIFGESGDEEEEE 492

  Fly  1083 ---------EDENGVSAAAKEE 1095
                     |:|.|.:...:.|
Human   493 FTGFNQEDLEEEKGETQVKEAE 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cp190	NP_524359.2	BTB	20..122	CDD:279045
		BTB	31..127	CDD:197585
		C2H2 Zn finger	540..568	CDD:275371	6/16 (38%)
		C2H2 Zn finger	569..586	CDD:275371	2/16 (13%)
IWS1	XP_005263764.1	Opi1	233..>337	CDD:285782	29/142 (20%)
		TFIIS_I	<533..797	CDD:294098

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153186
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930