Protein Alignment Cp190 and CG13185

DIOPT Version :10

• Sequence 1: NP_524359.2
• Gene: Cp190 / 41848
• FlyBaseID: FBgn0000283
• Length: 1096
• Species: Drosophila melanogaster
• Sequence 2: NP_001097279.2
• Gene: CG13185 / 36268
• FlyBaseID: FBgn0033661
• Length: 5526
• Species: Drosophila melanogaster
• Alignment Length: 1220
• Identity: 240/1220 - (19%)
• Similarity: 429/1220 - (35%)
• Gaps: 318/1220 - (26%)

  Fly    18 QKLQNFFNKTDYC-DLTLQFRDNSQLKVHRLVLSACTDY-FNVLEQTCEIVD--DALIMPNEFQA 78
            :||:.|.....|. ||:.....||...|||.:.....:| .::.|:..|:..  |:......|..
  Fly  3975 KKLKEFVKIQSYSKDLSYFSMRNSVASVHRNLNKFLKEYRLSIQEKISEVFQPKDSTAKDYTFGT 4039

  Fly    79 DVVVPI-----VNFMYTGTLEF--ELKMYGKLLRTAKEMNMTVLLKLLEAHRRTMENVNRQQRPP 136
            |....:     :.:::|...:|  ..|:..|.....:.::...||:.|:.|.||..:|.::....
  Fly  4040 DKGKGLRNYNKIKYLHTERQQFVASEKLLEKFAIQEEFLSDNTLLQRLDKHFRTARHVVKETLGQ 4104

  Fly   137 SPKG-------------------IRRRTVGQPSSGLPQQR-----VLGPSPQSRNVATPIAQR-- 175
            .|.|                   :|...|.: |...|||:     :|   .|.|...|.:.:.
  Fly  4105 VPYGELITELDDLLASQLERCEHLRSLNVDR-SKERPQQKQEAKQIL---QQKRKALTDLFKMLH 4165

  Fly   176 ---ANTQRGSTGNTMSRTSGGSNRSPYGDSSNV-KQEPTSP--FEQLRKGYNNN---KRPAQTSL 231
               ||.:.|....::..........||...|.: :..||:.  .|.|...|..:   .:..|..:
  Fly  4166 RLGANYKTGLLELSLRNEFEDFQLPPYSIRSMLPRLHPTAQQLDEHLDLYYMKSVFKLKLLQNIM 4230

  Fly   232 LSPPSK--KPSLEEVKEFA-------EQQRMRKQIAAEYGDNDPEYDGGMLYDDVHAGDDDDD-- 285
            |:|.|:  .|::|.:|.||       :|||              |:..|.. .::|...:..|
  Fly  4231 LTPLSELGPPNIERIKGFAVDLFLLVQQQR--------------EHLSGST-KELHELRNSLDSL 4280

  Fly   286 ----DMPPQ----PSTSKQQSPQGTQTQLEHGSTTI--ILKQDS--PSQTPTIIVKDSSN----- 333
                ::.||    |||...........:::.....|  :|||..  .|..|:..:::|.|
  Fly  4281 RKLAEIIPQADINPSTLNFVKSADIAMEIKQHLRQIHYVLKQWKLLLSCAPSSFIEESENRLLVR 4345

  Fly   334 ----AKLNHTKIIAEVLRQYPHIVKGHKNIKLKIMPNTPAAPTEKS----------APATVKPPA 384
                |:.....:..::|.....::....|..|:.:.:......:||          ....::...
  Fly  4346 KISLAQSELHSLCIQILNSSQELLNELNNANLEYLSSEKCVTYQKSYAEIQENIKKTLELLRTGQ 4410

  Fly   385 NQSSATTSPHKKL--HVSFK------------ADKSTPLITAQQKAASSQQK-----SGTSQTTG 430
            |.......|..:|  .|..|            |:..|.|.........|.||     ..|.:...
  Fly  4411 NDYLPLAQPIVELLDSVQLKNHTEIAPEAIDLANADTELANIAHSVLMSMQKIYKHHVKTDEVNQ 4475

  Fly   431 NQGTGANPPANTAAAQKRRIDSKTMHALIAQGAE-----NTTGPWLCLRCGVNGRPISIPSYRGF 490
            |             .:.:..|.::..||..|..:     ..|..|         :.:|:|...|.
  Fly  4476 N-------------GEAKEQDEESKEALQEQHLKKCLTGELTSDW---------QQLSLPRVLGK 4518

  Fly   491 RRHLI----NTHKETIDPALCEHCGWRSVNNRELHFHMYMEHQTKSLLYTFAECALCNQ--SYRT 549
            ..:::    ::|.|..|..||.        .|.:.....:|..  .||   |:..|..|  :::.
  Fly  4519 LSNVLLVLKHSHFEGKDKLLCV--------RRAIGLLPVLEQY--QLL---ADYLLLQQLATHKV 4570

  Fly   550 KGELEAHINEVHTD-DNKQQCIYCNKVFEQELQLYRHMKSYHKEQALEDGIIDETDEEFLGSQDE 613
            ..::.:.:..|..: .:|..|:..:.:.::|.|..:..|: .:...||||..:....:.:.|:|:
  Fly  4571 SAKMLSIVLTVFVEIGSKGFCVPPDLMQDEEGQSKQESKN-GEGFGLEDGTGENDASDKIESEDQ 4634

  Fly   614 EEEA--------EGDEEQEP---EQTGKVRILSDISLPATSAITVQQAQQEQLQEEDVEQVQQEV 667
            .::|        ||| :|||   |:.|                 ::.:.....:.:|||:.:::
  Fly  4635 LDDAKRPEDRKDEGD-KQEPDCKEEKG-----------------IEMSDDFDAKMQDVEKPEED- 4680

  Fly   668 KFVGADGNEVELTDEQRKEILSQLNQQQAGATAGGVVMVLSEPEAEHVKQETDEKSLAGTEEEYD 732
                 |..|.|..::..||:                      .|.|...::.|::.....|||..
  Fly  4681 -----DSGESEEEEDLNKEM----------------------GETEEGAEKLDDQIWGDDEEEKP 4718

  Fly   733 DSQIYSELGAADSVESAKKNIADESKESIDNLEWAENLIAESEEQSNKEPKSDKPRDDISEKLKE 797
            :.:           :....|..|:.|.|.|..:...:|  :::..:.||...|:...|..:...|
  Fly  4719 EEE-----------QEPDMNEEDQGKGSKDEKDAHNDL--DTKNDAAKEDGKDEHEKDGLDATNE 4770

  Fly   798 LTGDWTEDENDDDVDDKPATAELASELANKDPEPTVHEEEDDIDLALQSLHKGPEEATE-EKASE 861
            .:|:....|...|:||.            ||||  :.||:.:      ::|...||..| |:...
  Fly  4771 PSGEDKRKEQAKDIDDM------------KDPE--MDEEQTN------AMHNELEEPPEPEEMDL 4815

  Fly   862 ESVTSADDAVDAVPNINSQPEKMDVDSEAADEK-----ASKAEVQIKKEAELENDQEEFIKEDSP 921
            ..:.:.|:..|            |.|.:..||.     |.|..:|..:|.|.:.|.|....|:..
  Fly  4816 GDMNNVDEGHD------------DQDEQPTDENPFDIDAMKENMQPAEEPEADGDDEHDANEEGD 4868

  Fly   922 IPHSD-SVAELREAVTASEGEDDVHLEADNIRKELLDELIAEAEKPDQEKDIVQSEENATTEALD 985
             |.|| |.:|..||.|.::..::.|.|             .|...|:.|||..::::....|
  Fly  4869 -PQSDGSDSEEDEAGTEAKPAEEDHGE-------------GEEATPEDEKDEAETQKRGELE--- 4916

  Fly   986 RSVTDEDDLVPPTQVSTEQMEIDEPAAEKAAENNEDTRTADEKEAVEDKPNQTQ-----DVTTAE 1045
                ||||..|.......:.|.:|...||..|:::....|.::|.|:..|...|     .|...:
  Fly  4917 ----DEDDSKPEDSPEDSKEEKEEKREEKPEEHSQSKDKASKEENVQSMPETDQSSSADQVQQPQ 4977

  Fly  1046 KPTLESAKAGDEATSGEAASVDKVKSLISEWGDDDEDEDENGVSAAAKEE 1095
            .|.::..:..||..:||  ..|.|       |..:.|.|:.|....|:.:
  Fly  4978 DPDIKQDQKLDEQETGE--EKDGV-------GQAENDADDGGHQGVAETQ 5018

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cp190	NP_524359.2	BTB_POZ_CP190-like	16..125	CDD:349620	25/117 (21%)
		COG5236	<471..>594	CDD:227561	21/129 (16%)
		C2H2 Zn finger	540..568	CDD:275371	4/30 (13%)
		C2H2 Zn finger	569..586	CDD:275371	3/16 (19%)
		PTZ00121	<709..1075	CDD:173412	86/377 (23%)
CG13185	NP_001097279.2	P-loop containing Nucleoside Triphosphate Hydrolases	315..505	CDD:476819
		AAA_lid_7	523..653	CDD:465540
		AAA_7	741..>787	CDD:463698
		P-loop containing Nucleoside Triphosphate Hydrolases	<887..972	CDD:476819
		AAA_lid_5	985..1087	CDD:407722
		P-loop containing Nucleoside Triphosphate Hydrolases	1147..1283	CDD:476819
		AAA_lid_7	1295..1389	CDD:465540
		AAA_5	1454..1603	CDD:400191
		McrB	1641..>1887	CDD:441011
		MoxR	1785..>1951	CDD:440478
		AAA_lid_7	2007..2105	CDD:465540
		MDN1	<4592..5252	CDD:444083	117/549 (21%)
		vWA_midasin	5261..5526	CDD:238737