DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cp190 and IBSP

DIOPT Version :9

Sequence 1:	NP_524359.2	Gene:	Cp190 / 41848	FlyBaseID:	FBgn0000283	Length:	1096	Species:	Drosophila melanogaster
Sequence 2:	NP_004958.2	Gene:	IBSP / 3381	HGNCID:	5341	Length:	317	Species:	Homo sapiens

Alignment Length:	294	Identity:	62/294 - (21%)
Similarity:	101/294 - (34%)	Gaps:	93/294 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   560 VHTDDNKQQCIYCNKVFEQELQLYRHMKSY-HKEQALEDGIIDETDEEFLGSQDEEEEAE----- 618
            |..:|:::..::   .:.....||:|...| |.::....|..|.::|....|.:||||.|
Human    26 VKIEDSEENGVF---KYRPRYYLYKHAYFYPHLKRFPVQGSSDSSEENGDDSSEEEEEEEETSNE 87

  Fly   619 --------GDEEQEPEQ--------------------TGKVRILSDISLPATSAITVQQAQQEQL 655
                    .||:.|.|.                    ||    |:.|.||..:.....:|.:|
Human    88 GENNEESNEDEDSEAENTTLSATTLGYGEDATPGTGYTG----LAAIQLPKKAGDITNKATKE-- 146

  Fly   656 QEEDVEQVQQEVKFVGADGNEVELTDEQRKEILSQLNQQQAGATAGGVVMVLSEPEAEHVK---- 716
            :|.|.|:.::|      :|||.|.::.:..|     |:|....|:      .:..|||:..
Human   147 KESDEEEEEEE------EGNENEESEAEVDE-----NEQGINGTS------TNSTEAENGNGSSG 194

  Fly   717 ----QETDEKSLAGTEEEYDDSQIYSELGAADSVESAKKNIADE---------------SKESID 762
                :|.:|:|:.|...|  |:......|...|..:...|...|               .|.:..
Human   195 GDNGEEGEEESVTGANAE--DTTETGRQGKGTSKTTTSPNGGFEPTTPPQVYRTTSPPFGKTTTV 257

  Fly   763 NLEWAENLIAESE--------EQSNKEPKSDKPR 788
            ..|........:|        |..|.||:.|..|
Human   258 EYEGEYEYTGANEYDNGYEIYESENGEPRGDNYR 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cp190	NP_524359.2	BTB	20..122	CDD:279045
		BTB	31..127	CDD:197585
		C2H2 Zn finger	540..568	CDD:275371	2/7 (29%)
		C2H2 Zn finger	569..586	CDD:275371	2/16 (13%)
IBSP	NP_004958.2	BSP_II	17..314	CDD:283165	62/294 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	58..254		46/220 (21%)
		cell-attachment tripeptide	286..288		0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900