DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cp190 and Iws1

DIOPT Version :9

Sequence 1:	NP_524359.2	Gene:	Cp190 / 41848	FlyBaseID:	FBgn0000283	Length:	1096	Species:	Drosophila melanogaster
Sequence 2:	XP_006254633.1	Gene:	Iws1 / 291705	RGDID:	1304762	Length:	765	Species:	Rattus norvegicus

Alignment Length:	534	Identity:	110/534 - (20%)
Similarity:	202/534 - (37%)	Gaps:	139/534 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   589 YHKEQALEDG----IIDETDEEFLGSQDEEEEAEG------DEEQEPEQTG------KVRILSDI 637
            |:.....:||    :.||.|....|..|..|:..|      |...|.|.:.      |:...:|.
  Rat     5 YYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVDRHSENETSDREDGLTKIHNGTDS 69

  Fly   638 SLPATSAITVQQAQQEQL-QEEDVEQVQQEVKFVGADGNEVEL-----TDEQRKEIL----SQLN 692
            .....|.:....::.|:| :.:|.:...:|.....|..:|.|.     :|.:::|:|    |...
  Rat    70 ENDEPSNVHASDSESEELHRPKDSDSESEEHAESPASDSENEAVHQQGSDSEKEELLNGHASDSE 134

  Fly   693 QQQAGATAGGVVMVLSEPEAEHVKQETDEKSLAGTEEEYDDSQIYSELGAADSVESAKKNIADES 757
            :::....|.      |:.|.|...|.      .|:|.:.:|.. ..:...::|.|..|..|:|..
  Rat   135 KEEGRKHAA------SDSETEDTLQP------QGSESDSEDPP-RPQASDSESEEPPKPRISDSE 186

  Fly   758 KESIDNLEWAENLIAESEEQSNKEPKSDKPRDDISE-KLKELTGDWTEDENDDDVDDKPATAELA 821
            .|     |..:..|::||.:       |.||..:|: :.:||......|...:|.....|:...:
  Rat   187 SE-----ELPKPRISDSESE-------DPPRPQVSDSESEELPKPRVSDSESEDPPRPQASDSES 239

  Fly   822 SELANKDPEPTVHEEEDDIDLALQSLHKGP------EEATEEKASEESVTS-------------- 866
            .||    |:|.|.:.|.      :...|||      |:|:..|...||..|
  Rat   240 EEL----PKPRVSDSES------EDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNE 294

  Fly   867 ADDAVD-----AVPNINSQPEKMDVDSEAADEKASKAEVQIKKEAELENDQEE---------FIK 917
            :|...|     :..:...:|::..:||:...||....:|..:|.|.|.:.::|         .:.
  Rat   295 SDGHADRKGLHSSDSEEEEPKRQKIDSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAAKKSRVI 359

  Fly   918 EDSPIPHSDSVAE---LREAVTASEGEDDVHLEADNIRKELLDELIAEAEKPDQEKDIVQSEENA 979
            .|:....||.|::   .||...||:.|::|..|..:::|             .:|||:..|:..:
  Rat   360 SDADDSDSDVVSDKSGKREKTVASDSEEEVGKEESSVKK-------------SEEKDLFGSDSES 411

  Fly   980 TTEALDRSVTDEDDLVPPTQVSTEQMEIDEPAAE---KAAENNEDTRTADEKEAVEDKPNQTQDV 1041
            ..|        |::|:                |:   ::.:..|:..|...:|.:|::.|:||..
  Rat   412 GNE--------EENLI----------------ADIFGESGDEEEEEFTGFNQEDLEEEKNETQLK 452

  Fly  1042 TTAEKPTLESAKAG 1055
            ...:..:.::.|.|
  Rat   453 EAEDSDSDDNIKRG 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cp190	NP_524359.2	BTB	20..122	CDD:279045
		BTB	31..127	CDD:197585
		C2H2 Zn finger	540..568	CDD:275371
		C2H2 Zn finger	569..586	CDD:275371
Iws1	XP_006254633.1	MDN1	<30..402	CDD:227596	86/419 (21%)
Iws1	XP_006254633.1	TFIIS_I	<474..738	CDD:412184
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346797
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930