DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cp190 and Dmp1

DIOPT Version :9

Sequence 1:	NP_524359.2	Gene:	Cp190 / 41848	FlyBaseID:	FBgn0000283	Length:	1096	Species:	Drosophila melanogaster
Sequence 2:	XP_006250684.1	Gene:	Dmp1 / 25312	RGDID:	2508	Length:	504	Species:	Rattus norvegicus

Alignment Length:	553	Identity:	107/553 - (19%)
Similarity:	207/553 - (37%)	Gaps:	110/553 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   546 SYRTKGELEAHINEVHTDDNKQQCIYCNKVFEQELQLYRHMKSYHKEQALEDGIIDETDEEFLGS 610
            |..:|...|...|..|||.::.     .:....:...||......|...::..  .|.||:..|.
  Rat    50 SEESKVSPEGQANSDHTDSSES-----GEELGSDRSQYRPAGGLSKSAGMDAD--KEEDEDDSGD 107

  Fly   611 QDEEEEAEGDEEQEPEQTGKVRILSDISLPATSAITVQQAQQEQLQEEDVEQVQQEVKFVGADGN 675
            ....:|..|...:|.:..|..|:.||    ..||.|.|.::....||...:....:.|    |.:
  Rat   108 DTFGDEDNGPGPEERQWGGPSRLDSD----EDSADTTQSSEDSTSQENSAQDTPSDSK----DHH 164

  Fly   676 EVELTDEQRKEILSQLNQQQAGATAGGVVMVLSEPEAEHVKQETDEKSLAGTEEEYDDSQIYSEL 740
            ..|..........:|.::.:.....||     ||.|:.|           |...|:||..:.|
  Rat   165 SDEADSRPEAGDSTQDSESEEYRVGGG-----SEGESSH-----------GDGSEFDDEGMQS-- 211

  Fly   741 GAADSVESAKKNIADESKESIDNLEWAENLIAESEEQSNKEPKSDKPRDDISEKLKELTGDWTED 805
               |...|.:.:.......|..        |...|.:.:.||.|                  |:|
  Rat   212 ---DDPGSTRSDRGHTRMSSAG--------IRSEESKGDHEPTS------------------TQD 247

  Fly   806 ENDDDVDDKPATAELASELANKDPEPTVHEEEDDIDLALQSLHKGPEEATEE-KASEESVTSADD 869
             :||..|     .|.:|..:.:  ...|.||:|..:||..:..:...::||: ::.|||.:...:
  Rat   248 -SDDSQD-----VEFSSRKSFR--RSRVSEEDDRGELADSNSRETQSDSTEDFRSKEESRSETQE 304

  Fly   870 AVDAVPNINSQPEKMDVDSEAADEKASKAEVQIKKEAELENDQEEFIKEDSPIPHSDSVAELREA 934
            ......:....||..|..||:::|....::       |..::.:|.:..:|...:.|:.::..:.
  Rat   305 DTAETQSQEDSPEGQDPSSESSEEAGEPSQ-------ESSSESQEGVASESRGDNPDNTSQTGDQ 362

  Fly   935 VTASEGEDDVHLEADNIRKELLDELIAEAEKPDQEKDIVQSEENATTEALDRSVTDEDDLVPPTQ 999
            ..:...|:|          .|.....:|::..:::.|...:|..:.:|....|..|||
  Rat   363 RDSESSEED----------RLNTFSSSESQSTEEQGDSESNESLSLSEESQESAQDED------- 410

  Fly  1000 VSTEQMEIDEPAAEKAAENNEDTRTADEKEAVEDKPNQTQDVTTAEKPTLESAKAGDEATSGE-- 1062
             |:.|..:...:|.:.:.:.| :::..:..:.|::.:.:||.:.:::   ||...|..::|.|
  Rat   411 -SSSQEGLQSQSASRESRSQE-SQSEQDSRSEENRDSDSQDSSRSKE---ESNSTGSTSSSEEDN 470

  Fly  1063 ---AASVDKVKSLISEW-----GDDDEDEDENG 1087
               ....|..|.::..:     ||.|:::.::|
  Rat   471 HPKNIEADNRKLIVDAYHNKPIGDQDDNDCQDG 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cp190	NP_524359.2	BTB	20..122	CDD:279045
		BTB	31..127	CDD:197585
		C2H2 Zn finger	540..568	CDD:275371	7/21 (33%)
		C2H2 Zn finger	569..586	CDD:275371	2/16 (13%)
Dmp1	XP_006250684.1	DMP1	1..504	CDD:284637	107/553 (19%)
Dmp1	XP_006250684.1	PHA02664	<112..195	CDD:177447	21/95 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900