Protein Alignment Cp190 and TCHHL1

DIOPT Version :9

• Sequence 1: NP_524359.2
• Gene: Cp190 / 41848
• FlyBaseID: FBgn0000283
• Length: 1096
• Species: Drosophila melanogaster
• Sequence 2: NP_001008536.1
• Gene: TCHHL1 / 126637
• HGNCID: 31796
• Length: 904
• Species: Homo sapiens
• Alignment Length: 1031
• Identity: 206/1031 - (19%)
• Similarity: 351/1031 - (34%)
• Gaps: 292/1031 - (28%)

  Fly    43 KVHRLVLSACTDYF-----NVLEQTCEIVD---DALIMPNEFQADVVVPIVNFMYTGTLEFELKM 99
            ::.:|:.....|:|     :.:|:...:::   :.:|..:||    |:.|.|.:....|:.
Human    32 ELKQLIQGEFGDFFQPCVLHAVEKNSNLLNIDSNGIISFDEF----VLAIFNLLNLCYLDI---- 88

  Fly   100 YGKLLRTAKEMNMTVLLKLLEAHRRTMENVNRQQRPPSPKGIRRRTVGQPSSGLPQQRVLGPSPQ 164
                    |.:..:.|.::.:..:..:::|:.|    :..|..:.|||  :|...::|:| ||..
Human    89 --------KSLLSSELRQVTKPEKEKLDDVDVQ----ATTGDGQWTVG--TSPTQEKRML-PSGM 138

  Fly   165 SRNVATPIAQRANTQRGSTGNT----------------MSRTSGGSNRSPYGD--SSNVKQ--EP 209
            :.:     :|....:.|:.||.                .|..:...|:...||  |..|.|  :.
Human   139 ASS-----SQLIPEESGAVGNNRVDPWREAKTHNFPGEASEHNDPKNKHLEGDEQSQEVAQDIQT 198

  Fly   210 TSPFE-QLRKGYNNNKRPAQTSLLSPPSKKPSLEEVKEFAEQ--QRMRKQIAAEYGDNDPEYDGG 271
            |...| ||:    .||..|.:...|.|:::...:  ||.:::  :..|:|..::..|...|.:|.
Human   199 TEDNEGQLK----TNKPMAGSKKTSSPTERKGQD--KEISQEGDEPAREQSVSKIRDQFGEQEGN 257

  Fly   272 MLYDDVHAGDDDDDDMPPQPSTSKQQSPQGTQTQLEHGST---TIILKQD--------------- 318
            :.          ....||:.:|.:....|..:|:.|..|.   ..:.::|
Human   258 LA----------TQSSPPKEATQRPCEDQEVRTEKEKHSNIQEPPLQREDEPSSQHADLPEQAAA 312

  Fly   319 -SPSQTPTIIVKDSSNAKLNHTKIIAEVLRQYPHIVKGHKNIKLKIMPNTPAAPTEKSAPATVKP 382
             |||||     :.|:::|        :|.|.:.....|      |....|||.......|...
Human   313 RSPSQT-----QKSTDSK--------DVCRMFDTQEPG------KDADQTPAKTKNLGEPEDY-- 356

  Fly   383 PANQSSATTSPH---KKLHVSFKADKSTPLITAQQKAASSQQKSGTSQTTGNQGTGANPPANTAA 444
              .::|.|....   |.|.|.:                .|:..|.||.....:.....|.|:..|
Human   357 --GRTSETQEKECETKDLPVQY----------------GSRNGSETSDMRDERKERRGPEAHGTA 403

  Fly   445 AQKRRIDSKTMHALIAQGAENTTGPWLCLRCGVNGRPISIPSYRGFRRHLIN------THKETID 503
            .||.| |.||...::.  .:...|.:..|:    |...|..:.:|.....::      ||.|...
Human   404 GQKER-DRKTRPLVLE--TQTQDGKYQELQ----GLSKSKDAEKGSETQYLSSEGGDQTHPELEG 461

  Fly   504 PALCEHCGWRSVNNRELHFHMYMEHQTKSLLYTFAECALCNQSYRTKGELEAHINEVHTDD---- 564
            .|         |:..|      .||..:.....|........:.||.|..|      .|.|
Human   462 TA---------VSGEE------AEHTKEGTAEAFVNSKNAPAAERTLGARE------RTQDLAPL 505

  Fly   565 NKQQCIYCNKVFEQELQLYRHMKSYHKEQALEDGIIDETDEEFLGSQDEEEEAE------GDEEQ 623
            .||      .|.|..    |..|::.:....|||...| |.|...:|.:|..:|      .:|..
Human   506 EKQ------SVGENT----RVTKTHDQPVEEEDGYQGE-DPESPFTQSDEGSSETPNSLASEEGN 559

  Fly   624 EPEQTGKVRILSDISLPATSAITVQQAQQEQLQE----------------------EDVEQVQQE 666
            ...:||::.:..|           .|:|.:|..|                      ..:|.|...
Human   560 SSSETGELPVQGD-----------SQSQGDQHGESVQGGHNNNPDTQRQGTPGEKNRALEAVVPA 613

  Fly   667 VKFVGADGNEVELTDEQRKEILSQLNQQQAGATA-GGVVMVLSEPEA-EHVKQETDEKSL----- 724
            |:     |.:|:||::|.:....:...|..|... |..|.....||| |....:.:.|||
Human   614 VR-----GEDVQLTEDQEQPARGEHKNQGPGTKGPGAAVEPNGHPEAQESTAGDENRKSLEIEIT 673

  Fly   725 AGTEEEYDDSQIYSEL-GAADSVESAKKNIADESKESIDNLEWAENLIAESEEQSN--------- 779
            ...:|::.|.....:| |..||....|.. ...|||.......|:|.:.||.::.|
Human   674 GALDEDFTDQLSLMQLPGKGDSRNELKVQ-GPSSKEEKGRATEAQNTLLESLDEDNSASLKIQLE 737

  Fly   780 -KEPKSDKPRDDISEKLKELTGD--------------WTEDENDDDVDDKPATAELAS------- 822
             |||.:.:..|:..::|....||              |:..|.....|.:|.:.|..:
Human   738 TKEPVTSEEEDESPQELAGEGGDQKSPAKKEHNSSVPWSSLEKQMQRDQEPCSVERGAVYSSPLY 802

  Fly   823 ----ELANKDPEPTVHEEEDDIDLALQSLHKGPEEATEEKASEESVTSADDAVDAVPNINSQPEK 883
                |...:....|..|.:..:.:|..|   |||..:....||.|    |.:|....:..|||..
Human   803 QYLQEKILQQTNVTQEEHQKQVQIAQAS---GPELCSVSLTSEIS----DCSVFFNYSQASQPYT 860

  Fly   884 MDVDSEAADEKASKAEVQIKKEAELENDQEEFIKEDSPIPHSDSVAELREAVTASE 939
            ..:   ..||..:.|:         |....:.:::....|..:.:...|||.|..:
Human   861 RGL---PLDESPAGAQ---------ETPAPQALEDKQGHPQRERLVLQREASTTKQ 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cp190	NP_524359.2	BTB	20..122	CDD:279045	13/86 (15%)
		BTB	31..127	CDD:197585	13/91 (14%)
		C2H2 Zn finger	540..568	CDD:275371	7/31 (23%)
		C2H2 Zn finger	569..586	CDD:275371	3/16 (19%)
TCHHL1	NP_001008536.1	S-100	2..88	CDD:238131	11/59 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..792		167/812 (21%)
		MDN1	<170..599	CDD:331582	107/533 (20%)
		Na_Ca_ex	<502..757	CDD:332332	62/282 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	858..890		6/43 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153189
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930