DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cp190 and zbtb47

DIOPT Version :9

Sequence 1:	NP_524359.2	Gene:	Cp190 / 41848	FlyBaseID:	FBgn0000283	Length:	1096	Species:	Drosophila melanogaster
Sequence 2:	XP_004915642.1	Gene:	zbtb47 / 100489594	XenbaseID:	XB-GENE-992955	Length:	733	Species:	Xenopus tropicalis

Alignment Length:	640	Identity:	122/640 - (19%)
Similarity:	215/640 - (33%)	Gaps:	199/640 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 QNFFNKTDYCDLTLQF-RDNSQLKVHRLVLSACTDYFNVL------EQTCEIVDDALIMPNEFQA 78
            |..| :.|.||:.:.. :..|....|:.||:|.:.:|:.|      .|..|:..:|| ....||
Frog    35 QRLF-QPDLCDVDIVLVQQKSTFPAHKGVLAAYSQFFHSLFTQNKQLQRVELSLEAL-TSRGFQ- 96

  Fly    79 DVVVPIVNFMYTGTLEFE-------------LKMYGKLLRTAKE------MNMTVLLKLLEAH-- 122
                .|:||:||..|...             |:| .:::.:.:|      :|:::...:|||.
Frog    97 ----QILNFIYTSKLLVNGCNVQDVLNAAAVLQM-NEIVTSCQELIHSRSLNLSMANDILEAEDT 156

  Fly   123 RRTMENVN--------RQQRPPSPKGIRRRTVGQPSSGLPQQRVL-GPSPQSRNVATPIAQRANT 178
            |.....|.        :|:....|..|..|....|.|...:..|. |..|   |.::|.....:.
Frog   157 RNDTPTVMPPQFYREIKQEVDAPPTKIYAREGNDPYSVRVEDSVTKGHLP---NTSSPKQYFKDE 218

  Fly   179 QRGSTGNTMSRTSGGSNRSPYGDSSNVKQEPTSPFEQLRKGYNNNKRPAQTSLLSPPSKKPSLEE 243
            :|  :|..:.:..||.:      ..:::.:.:...||:....|.|.:....|  .....|.|.|.
Frog   219 ER--SGQRVCKIEGGDS------EEDIESQESFNREQIIVEVNLNNQTLNVS--KGTDGKGSSEP 273

  Fly   244 VKEFAEQQRMRKQIAAEYGDNDPEYDGGMLYDDVHAGDDDDD--DMPPQPSTSKQQSPQGTQTQL 306
            |..........:....:..|.:.|.:||:        :::||  ||.........||....:...
Frog   274 VTVLDRSDGDDRGSEEDGDDENEEEEGGL--------EEEDDFLDMLEDEEDEGMQSDDDNEESR 330

  Fly   307 EHGSTTIILKQDSPSQTPTIIVKDSSNAKLNHTKIIAEVLRQYPHIVKGHKNIKLKIMPNTPAAP 371
            |         :|..:.....|.||.::|
Frog   331 E---------EDRDNDETEEIAKDENSA------------------------------------- 349

  Fly   372 TEKSAPATVKPPANQSSATTSPHKKLHVSFKADKSTPLITAQQKAASSQQKSGTS----QTTGNQ 432
             |:.:|:    |::                  ||:|.| |...|...:|:.:|.|    :..|..
Frog   350 -EEESPS----PSD------------------DKATKL-TKGSKGTRNQRGAGGSGRRKKKGGQD 390

  Fly   433 GTGANPPANTAAAQKRRIDSKTMHALIAQGAENTTGPWLCLRCGVNGRPISIPSYRGFRRHLINT 497
            |.|          ||.:.:.|          :|    :.|.:|     |....:.....:|:..|
Frog   391 GVG----------QKGKFEEK----------QN----FPCKKC-----PRVFNNRWYLEKHMNVT 426

  Fly   498 HKETIDPALCEHCGWRSVNNRELHFH--------------------MYMEHQTKSLLYTFAE--- 539
            |...   .:|:.||.|.:...||..|                    ::..|:...:::.:||
Frog   427 HSRM---RICDKCGKRFLLESELMLHHQTDCEKNIQCLTCGKTFKKLWSLHEHNKIVHGYAEKKF 488

  Fly   540 -CALCNQSYRTKGELEAHINEVHTDDNKQQCIYCNKVFEQELQLYRHMKSYHKEQ 593
             |.:|.:.:.|...:..|: ..||.|....|..|.|.|::.:.|..|...:..|:
Frog   489 SCDICEKKFYTMAHVRKHL-VAHTKDMPFTCETCGKSFKRSMSLKVHSLQHSGEK 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cp190	NP_524359.2	BTB	20..122	CDD:279045	30/126 (24%)
		BTB	31..127	CDD:197585	28/123 (23%)
		C2H2 Zn finger	540..568	CDD:275371	7/27 (26%)
		C2H2 Zn finger	569..586	CDD:275371	5/16 (31%)
zbtb47	XP_004915642.1	BTB_POZ_ZBTB47_ZNF651	29..143	CDD:349540	27/115 (23%)
		2A1904	<216..356	CDD:273344	31/208 (15%)
		CobT2	<309..>359	CDD:226920	13/118 (11%)
		PLN03086	<399..493	CDD:178635	19/115 (17%)
		C2H2 Zn finger	406..427	CDD:275370	4/25 (16%)
		C2H2 Zn finger	433..452	CDD:275368	7/18 (39%)
		C2H2 Zn finger	460..480	CDD:275368	1/19 (5%)
		C2H2 Zn finger	490..510	CDD:275368	4/20 (20%)
		C2H2 Zn finger	518..538	CDD:275368	6/19 (32%)
		SFP1	<540..626	CDD:227516	1/3 (33%)
		C2H2 Zn finger	546..566	CDD:275368
		C2H2 Zn finger	574..594	CDD:275368
		COG5048	601..>650	CDD:227381
		C2H2 Zn finger	605..625	CDD:275368
		C2H2 Zn finger	633..650	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24394
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100