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Protein Alignment Zip88E and SLC39A2

DIOPT Version :9

Sequence 1:	NP_650440.2	Gene:	Zip88E / 41847	FlyBaseID:	FBgn0038312	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_055394.2	Gene:	SLC39A2 / 29986	HGNCID:	17127	Length:	309	Species:	Homo sapiens

Alignment Length:	366	Identity:	88/366 - (24%)
Similarity:	137/366 - (37%)	Gaps:	108/366 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 VLAMLVLGLGSLLFGLLPA----FISERNRRRFPLTASLLLCFGAGILLATALVHILPEVREQMD 89
            :.|:|.|.||.   ||.|.    |..:..|....|...||.|..||:.|....:|:..|..|:::
Human    12 LFALLALTLGC---GLTPICFKWFQIDAARGHHRLVLRLLGCISAGVFLGAGFMHMTAEALEEIE 73

  Fly    90 SK----------------------------FAEVAMCGGFFIIYFIDEFIHYFFGEAIQHTHAHD 126
            |:                            :.|:.:..|||.::|::..       |:|..
Human    74 SQIQKFMVQNRSASERNSSGDADSAHMEYPYGELIISLGFFFVFFLESL-------ALQCC---- 127

  Fly   127 AETPATEPPRRPTNDNGYGAVDERAPLLSAEPNTSHGHSH---HHSHDHDHNHPASASGCNDASV 188
                       |....|....||           ..|.:|   .|||.|   .|:.:.|...|.|
Human   128 -----------PGAAGGSTVQDE-----------EWGGAHIFELHSHGH---LPSPSKGPLRALV 167

  Fly   189 EDANARICHTSHTEPCAQSMTGTLGLFVALSLHSAIEGLAIGVQNSSTKVLFLLGAVACHKFVMG 253
                                     |.::||.||..||||:|:|.:....:.|..||..||.::.
Human   168 -------------------------LLLSLSFHSVFEGLAVGLQPTVAATVQLCLAVLAHKGLVV 207

  Fly   254 FCLGLEFRSNPQTSFRAQFVGISVFALGAVIGIGLGMLIVDVPA-AWSSKTLPIVQALAGGTLFY 317
            |.:|:.. .:..||.|.....|.:.||.:.:|:.:|:.:....: ........:::.:|.||..|
Human   208 FGVGMRL-VHLGTSSRWAVFSILLLALMSPLGLAVGLAVTGGDSEGGRGLAQAVLEGVAAGTFLY 271

  Fly   318 VTVCEVIPREKARWHSNSTRRWAGFAQFATVLAGFATMCII 358
            ||..|::|||.|...       |..|:::.|.||||.|..|
Human   272 VTFLEILPRELASPE-------APLAKWSCVAAGFAFMAFI 305

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.