Protein Alignment Zip88E and SLC39A3

DIOPT Version :9

• Sequence 1: NP_650440.2
• Gene: Zip88E / 41847
• FlyBaseID: FBgn0038312
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_653165.2
• Gene: SLC39A3 / 29985
• HGNCID: 17128
• Length: 314
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 89/314 - (28%)
• Similarity: 136/314 - (43%)
• Gaps: 50/314 - (15%)

  Fly    28 KVLAMLVLGLGSLLFGLLPAFISERNRRRFPLTASLL-LC--FGAGILLATALVHILPEVREQM- 88
            |:|.|:.:....||..|||..|.|.:..:...:..:| ||  ||.|:.|||....:||.|||::
Human     8 KILCMVGVFFFMLLGSLLPVKIIETDFEKAHRSKKILSLCNTFGGGVFLATCFNALLPAVREKLQ 72

  Fly    89 ----------DSKFAEVAMCGGFFIIYFIDEFIHYFFGEAIQHTHAHDAETPATEPPRRPTNDNG 143
                      |...||..:..|||:..|:::.|..|..|.....   |.||      ....:|.|
Human    73 KVLSLGHISTDYPLAETILLLGFFMTVFLEQLILTFRKEKPSFI---DLET------FNAGSDVG 128

  Fly   144 YGAVDERAPLLSAEPNTSHGHSHHHSHDHDHNHPASASGCNDASVEDANARICHTSHTEPCAQSM 208
            ..: :..:|.:..    :.||: .:...|.|....|..|.:.||    ..|:
Human   129 SDS-EYESPFMGG----ARGHA-LYVEPHGHGPSLSVQGLSRAS----PVRL------------- 170

  Fly   209 TGTLGLFVALSLHSAIEGLAIGVQNSSTKVLFLLGAVACHKFVMGFCLGLEFRSNPQTSFRAQFV 273
               |.|..|||.||..||||:|:|....||:.|...||.|:.::...||:....:......|..:
Human   171 ---LSLAFALSAHSVFEGLALGLQEEGEKVVSLFVGVAVHETLVAVALGISMARSAMPLRDAAKL 232

  Fly   274 GISVFALGAVIGIGLGMLIVDVPAAWSSKTLPIVQALAGGTLFYVTVCEVIPRE 327
            .::|.|: ..:|||||:.|........|....::|.|||||..::|..|::.:|
Human   233 AVTVSAM-IPLGIGLGLGIESAQGVPGSVASVLLQGLAGGTFLFITFLEILAKE 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zip88E	NP_650440.2	Zip	26..359	CDD:280666	89/314 (28%)
SLC39A3	NP_653165.2	Zip	5..309	CDD:396884	89/314 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1558
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6210
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D471714at33208
OrthoFinder	1	1.000	-	-		FOG0000574
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5411
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.760