DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsynO and atp-3

DIOPT Version :9

Sequence 1:	NP_524358.2	Gene:	ATPsynO / 41845	FlyBaseID:	FBgn0016691	Length:	209	Species:	Drosophila melanogaster
Sequence 2:	NP_001021421.1	Gene:	atp-3 / 172195	WormBaseID:	WBGene00000230	Length:	228	Species:	Caenorhabditis elegans

Alignment Length:	203	Identity:	94/203 - (46%)
Similarity:	135/203 - (66%)	Gaps:	3/203 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLSRTLSSAAAQA---TVKPPVQVFGLEGRYATALYSAASKLSQLDQVEKDLTALQATIRSDKKL 70
            |:.|..|::||.|   .||.|:||.|:|||||.|||||..|.::|||:..||..:::..:.:||.
Worm    25 LMKRGFSTSAALAKAQLVKTPIQVHGVEGRYAAALYSAGHKQNKLDQISTDLNNVRSVYKDNKKF 89

  Fly    71 REYVTSPIINKKVMATALKEASEKLRFAPATVNLLGLLADNGRLKKLDTVINAYKTIMAAHRGEV 135
            :|:|..|.:......||::..|.||.....|.|.|||||:||||.||::|::::::||.|||||:
Worm    90 QEFVLDPTLKANKKKTAIEAISTKLGLTKETGNFLGLLAENGRLNKLESVVSSFESIMRAHRGEL 154

  Fly   136 VCEVVTAKPLDASQSKQLEGALKSFLKGNESLKITSRVDPSIIGGLIVSIGDKYVDMSIATKVKL 200
            ..:|.:|:.|.:|..|.|..||....|..:.|.:|..|.|||:|||:|:|||||||:|||::||.
Worm   155 FVQVTSAEELSSSNQKALSDALSKIGKSGQKLTVTYAVKPSILGGLVVTIGDKYVDLSIASRVKK 219

  Fly   201 YTDVIQTA 208
            |.|.:.||
Worm   220 YKDALATA 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsynO	NP_524358.2	OSCP	32..199	CDD:278635	76/166 (46%)
atp-3	NP_001021421.1	OSCP	51..224	CDD:278635	80/172 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167789
Domainoid	1	1.000	157	1.000	Domainoid score	I2540
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1283
Inparanoid	1	1.050	181	1.000	Inparanoid score	I2655
Isobase	1	0.950	-	0	Normalized mean entropy	S1100
OMA	1	1.010	-	-		QHG57719
OrthoDB	1	1.010	-	-		D1178688at2759
OrthoFinder	1	1.000	-	-		FOG0004090
OrthoInspector	1	1.000	-	-		oto17477
orthoMCL	1	0.900	-	-		OOG6_101031
Panther	1	1.100	-	-	LDO	PTHR11910
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R121
SonicParanoid	1	1.000	-	-		X3931
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890