DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Set and TSPYL5

DIOPT Version :9

Sequence 1:	NP_650438.2	Gene:	Set / 41844	FlyBaseID:	FBgn0014879	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_277047.2	Gene:	TSPYL5 / 85453	HGNCID:	29367	Length:	417	Species:	Homo sapiens

Alignment Length:	265	Identity:	90/265 - (33%)
Similarity:	144/265 - (54%)	Gaps:	45/265 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ADGNTSAAAGNNEEESE-----------ALEQIDACQNEIDALNEKASEEILKVEQKYNKLRKPC 68
            |..|||.:||..::|..           :::.::..|.:::.:|.:|....|::.:|:.:||...
Human   173 AGENTSVSAGEEKKEERDAGSGPPATEGSMDTLENVQLKLENMNAQADRAYLRLSRKFGQLRLQH 237

  Fly    69 YEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDIKSGYRINFHFDENP 133
            .|:|:.|::.||.||..:|.||||::..|:.:|:|.|..||.|||||....:.||:|.|:||.||
Human   238 LERRNHLIQNIPGFWGQAFQNHPQLASFLNSQEKEVLSYLNSLEVEELGLARLGYKIKFYFDRNP 302

  Fly   134 YFENKVLTKEFHLNSAAASENGDWPA----STSTPIKWKEGKNLLKLLLTKPYGNKKKRNSEYKT 194
            ||:||||.||:          |..|:    |.||||:|..|.:|..|....|..|        ::
Human   303 YFQNKVLIKEY----------GCGPSGQVVSRSTPIQWLPGHDLQSLSQGNPENN--------RS 349

  Fly   195 FFDWFSDNTDPVNDEIAELIKDDLWPNPLQYYLVPDIEVEPEDEEDNEDNDEEAFDDEDGEDGEG 259
            ||.|||:::...:|:|.|:|.::|||||||:||:            :|....|...:::|..|.|
Human   350 FFGWFSNHSSIESDKIVEIINEELWPNPLQFYLL------------SEGARVEKGKEKEGRQGPG 402

  Fly   260 EEEEE 264
            ::..|
Human   403 KQPME 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set	NP_650438.2	NAP	31..227	CDD:279323	75/210 (36%)
TSPYL5	NP_277047.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	93..112
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	127..202		7/28 (25%)
		NAP	205..382	CDD:415499	75/194 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	391..417		4/17 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152044
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1191764at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11875
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.810