DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Set and TSPYL1

DIOPT Version :9

Sequence 1:	NP_650438.2	Gene:	Set / 41844	FlyBaseID:	FBgn0014879	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_003300.1	Gene:	TSPYL1 / 7259	HGNCID:	12382	Length:	437	Species:	Homo sapiens

Alignment Length:	237	Identity:	79/237 - (33%)
Similarity:	132/237 - (55%)	Gaps:	28/237 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KRAKLDGAPADGNTSAAAGNNEEESEALEQ--------------IDACQNEIDALNEKASEEILK 56
            ::.:::..|.:|.....|..:..|.||.|:              ::|.|.|:|.:|.:|.....:
Human   188 EQMEVEEQPPEGEEIEVAEEDRLEEEAREEEGPWPLHEALRMDPLEAIQLELDTVNAQADRAFQQ 252

  Fly    57 VEQKYNKLRKPCYEKRSELVKRIPNFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDIKS 121
            :|.|:.::|:...|:|:.:::.||.||:|:|.||||:|.::..::.|.|..:..|||:|....::
Human   253 LEHKFGRMRRHYLERRNYIIQNIPGFWMTAFRNHPQLSAMIRGQDAEMLRYITNLEVKELRHPRT 317

  Fly   122 GYRINFHFDENPYFENKVLTKEFHLNSAAASENGDWPASTSTPIKWKEGKNLLKLLLTKPYGNKK 186
            |.:..|.|..||||.||::.||:.:.|:..      ..|.||||.|:.|.        :|....:
Human   318 GCKFKFFFRRNPYFRNKLIVKEYEVRSSGR------VVSLSTPIIWRRGH--------EPQSFIR 368

  Fly   187 KRNSEYKTFFDWFSDNTDPVNDEIAELIKDDLWPNPLQYYLV 228
            :......:||.||||::.|.:|:|||:||:|||||||||||:
Human   369 RNQDLICSFFTWFSDHSLPESDKIAEIIKEDLWPNPLQYYLL 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set	NP_650438.2	NAP	31..227	CDD:279323	73/209 (35%)
TSPYL1	NP_003300.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..81
TSPYL1	NP_003300.1	NAP	228..409	CDD:279323	70/194 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152057
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1191764at2759
OrthoFinder	1	1.000	-	-		FOG0000644
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11875
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.810