DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Set and Tspyl4

DIOPT Version :9

Sequence 1:	NP_650438.2	Gene:	Set / 41844	FlyBaseID:	FBgn0014879	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_084479.1	Gene:	Tspyl4 / 72480	MGIID:	106393	Length:	406	Species:	Mus musculus

Alignment Length:	225	Identity:	75/225 - (33%)
Similarity:	127/225 - (56%)	Gaps:	24/225 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 AGNNEEES-------EALEQIDACQNEIDALNEKASEEILKVEQKYNKLRKPCYEKRSELVKRIP 80
            ||..:||:       ..::.::|...|:..:|.:|....|::|:|:.::|:...::||.:::.||
Mouse   179 AGGGKEETRPRAPKINCMDSLEAIDQELSNVNAQADRAFLQLERKFGRMRRLHMQRRSFIIQNIP 243

  Fly    81 NFWVTSFINHPQVSGILDEEEEECLHALNKLEVEEFEDIKSGYRINFHFDENPYFENKVLTKEFH 145
            .||||:|.||||:|.::..::|:.:..:..|||||.:..:.|.:..|.|..||||.|:.|.||:.
Mouse   244 GFWVTAFRNHPQLSPMISGQDEDMMRYMINLEVEELKQPRVGCKFKFIFQSNPYFRNEGLVKEYE 308

  Fly   146 LNSAAASENGDWPASTSTPIKWKEGKNLLKLLLTKPYGNKKKRNSEYKTFFDWFSDNTDPVNDEI 210
            ..|:..      ..|.||||:|..|:.      .:.:.::.:..:...:||:||||::....|.|
Mouse   309 RRSSGR------VVSLSTPIRWHRGQE------PQAHIHRNREGNTIPSFFNWFSDHSLLEFDRI 361

  Fly   211 AELIKDDLWPNPLQYYLVPD-----IEVEP 235
            ||:||.:||.|||||||:.|     :.|.|
Mouse   362 AEIIKGELWSNPLQYYLMGDGPRRGVRVPP 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Set	NP_650438.2	NAP	31..227	CDD:279323	66/195 (34%)
Tspyl4	NP_084479.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..63
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	81..121
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..189		4/9 (44%)
		NAP	218..378	CDD:415499	62/171 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	387..406		2/5 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842142
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1191764at2759
OrthoFinder	1	1.000	-	-		FOG0000644
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11875
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.810